日本 CLEA Japan 普通饲料General Diets

日本 CLEA Japan 普通饲料General Diets
上海金畔生物代理日本CLEA Japan 公司饲料,欢迎客户访问CLEA Japan 官网或者咨询我们获取更多相关产品信息。

CA-1 (for breeding) CA-1(用于育种)
CE-2 (for rearing and breeding) Ce-2(用于饲养和育种)
CE-7 (for long-term rearing) CE-7(长期饲养)
CL-2 (for germ-free and immunodeficient animals) Cl-2(用于无菌和免疫缺陷动物)
B·F (for weaning) B·F(用于断奶)
Quick Fat (for diabetes and obesity research) 快速脂肪(用于糖尿病和肥胖研究)
High Fat Diet 32 (for diabetes and obesity researc) 高脂饮食32(糖尿病和肥胖研究)
CR-3 (for rearing) CR-3(用于饲养)
CG-7 (for rearing and breeding) CG-7(用于饲养和繁殖)
CD-5M (for breeding and rearing) 镉-5米(用于繁殖和饲养)
CMK-2 (for rearing) CMK-2(用于饲养)
CMS-1M (for breeding and rearing) CMS-1M(用于育种和饲养)
M-16 M-16

For mice, rats, and hamsters   对于老鼠、老鼠和仓鼠
OA-2
CA-1
CE-2
CE-7
CL-2
B・F
For diabetes and obesity studies (for mice and rats)   糖尿病和肥胖研究(老鼠和大鼠)
Quick Fat  快速脂肪
High Fat Diet 32     高脂饮食32
For rabbits and guinea pigs  兔和豚鼠
CR-3
CG-7
For dogs    狗饲料
CD-5M
For monkeys     猴子
CMK-2
CMS-1M
For miniature pigs 小型猪饲料
M-16

Research Diets D12108C 高脂饲料(含1.25%胆固醇)

Research Diets D12108C 高脂饲料(含1.25%胆固醇)
上海金畔生物代理Research Diets品牌饲料,欢迎客户访问Research Diets品牌官网或者咨询我们获取更多饲料价格等相关信息。
美国Research Diets公司是一家专业生产实验室动物饲料的顶尖公司,还可以根据客户要求定制特殊饲料,满足客户多方面需求。
Research Diets 公司是一家专业的生产科研实验室动物饲料的大型公司,产品包括高脂、高糖、脂肪肝、酒精肝、动脉硬化、缺铁性贫血饲料、骨质疏松饲料等饲料的世界著名的供应商。
Research Diets D12108C 高脂饲料(含1.25%胆固醇)
货号:D12108C
英文名:High fat rodent diet with 1.25% cholesterol
品牌:Research Diets
我司所销售的化学试剂、原料等所有产品(包括但不限于抗生素类、蛋白质类、试剂盒类产品等)仅限用于科学研究用途,不得作用于人体。

Description
High fat rodent diet with 1.25% cholesterol.
Used in Research
Atherosclerosis
Often used with Apo E or LDLR knockout mice
Replaces
D12108 with used alcohol-extracted casein, which is not believed to be important in inducing an athero phenotype.
Packaging
Product is packed in 12.5 kg box.
Each box is identied with the product name, description, lot number and expiration date.
Lead Time
5-7 business days.
Gamma-Irradiation
Yes. Add 10 days to delivery time.
Form
Pellet, Powder
Shelf Life
Most diets require storage in a cool dry environment. Stored correctly they should last 6 months.
Because of the high fat content is best if kept frozen.
Reference listing  参考文献:
  • Lichtman AH, Clinton S et al. Hyperlipidemia and Atherosclerosclerotic Lesion Development in LDL Receptor-Deficient Mice Fed Defined Semi purified Diets With and Without Cholate. Arteriosclerosis, Thrombosis and Vascular Biology. 1999; 19:1938-1944.
  • Cybulsky MI, Iiyama K, Li H, Zhu S, Chen M, Iiyama M, Davis V, Gutierrez-Ramos J-C, Connelly PW, & Milstone DS. A major role for VCAM-1, but not ICAM-1, in early atherosclerosis. J. Clin. Invest. 107:1255-1262, 2001.
  • Deguchi JO, Aikawa M, Tung CH, Aikawa E, Kim DE, Ntziachristos V, Weissleder R, Libby P. Inflammation in atherosclerosis: visualizing matrix metalloproteinase action in macrophages in vivo. Circulation. 2006 Jul 4;114(1):55-62. Epub 2006 Jun 26.
  • Xie D, Hazarika S, Andrich AJ, Padgett ME, Kontos CD, Donatucci CF, Annex BH. High cholesterol feeding in C57/Blc6 mice alters expression within the VEGF receptor-ligand family in corporal tissue. J Sex Med. 2008 May;5(5):1137-48.
  • Aslanian AM, Charo IF. Targeted disruption of the scavenger receptor and chemokine CXCL16 accelerates atherosclerosis. Circulation. 2006 Aug 8;114(6):583-90. Epub 2006 Jul 31.
  • Chiba T, Shinozaki S, Nakazawa T, Kawakami A, Ai M, Kaneko E, Kitagawa M, Kondo K, Chait A, Shimokado K. Leptin deficiency suppresses progression of atherosclerosis in apoE-deficient mice. Atherosclerosis. 2008 Jan;196(1):68-75. Epub 2007 Mar 23.
  • Martens GW, Arikan MC, Lee J, Ren F, Vallerskog T, Kornfeld H. Hypercholesterolemia impairs immunity to tuberculosis. Infect Immun. 2008 Aug;76(8):3464-72. Epub 2008 May 27.
  • Wolfrum S, Teupser D, Tan M, Chen KY, Breslow JL. The protective effect of A20 on atherosclerosis in apolipoprotein E-deficient mice is associated with reduced expression of NF-kappaB target genes. Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18601-6. Epub 2007 Nov 15.
  • Trogan E, Feig JE, Dogan S, Rothblat GH, Angeli V, Tacke F, Randolph GJ, Fisher EA. Gene expression changes in foam cells and the role of chemokine receptor CCR7 during atherosclerosis regression in ApoE-deficient mice. Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3781-6. Epub 2006 Mar 1.

日本 CLEA Japan品牌饲料 CLEA Rodent Diet CA-1 (for breeding)

日本 CLEA Japan品牌饲料 CLEA Rodent Diet CA-1 (for breeding)

CLEA Japan, Inc
This diet is a Good Laboratory Practice (GLP)-compliant diet consisting mainly of animal protein (whitefish meal) with a proper balance of cereals and enriched with protein content and minerals. This diet is designed for the breeding of inbred animals.
对于老鼠、老鼠和仓鼠–Clea啮齿动物日粮CA-1(用于繁殖)
这种饮食是一个良好的实验室实践(GLP)的饮食,主要由动物蛋白质(白粉)与适当的平衡谷类和丰富的蛋白质含量和矿物质。这种饮食是为繁殖近交系动物而设计的。

Ingredients Protein source whitefish meal, soybean meal, yeast, fish liver powder
Fat source cereal germ, soybean oil
Fiber source wheat bran, defatted rice bran, alfalfa meal
Carbohydrate source wheat flour, corn, milo
Vitamins Vit. A, D3, E, B1, B2, B6, B12, C, niacin, pantothenic acid, biotin, folic acid, choline chloride, inositol
Minerals calcium carbonate, salt, ferrous sulfate, manganese sulfate, cobalt sulfate, calcium iodate
Mean values from regular analyses in fiscal 2017
Nutrient components and calories
(in 100 g)
(All production lots analyzed)
Moisture (%) 8.48
Crude protein (%) 27.09
Crude fat (%) 4.69
Crude fiber (%) 4.54
Crude ash (%) 7.92
NFE (%)*1 47.28
Energy (kcal)*1,2 339.7
Hardness (kg/cm2) 24.7
*1Calculated from mean values.
*2Calculated by multiplying crude protein (4), crude fat (9), and NFE (4).
Minerals (in 100 g)
(All production lots analyzed for Ca and P. Other minerals subjected to semiannual analyses)
Ca (g) 1.54
P (g) 1.32
Mg (g) 0.32
K (g) 0.86
Mn (mg) 11.33
Fe (mg) 29.90
Cu (mg) 0.78
Zn (mg) 7.00
Na (g) 0.42
Ca/P*1 1.17
Ca/Mg*1 4.83
K/Na*1 2.07
*1Calculated from mean values.
Vitamin (in 100g)
(Semiannual analyses)
Retinol (IU) 2730
Vitamin B1 (mg) 1.9
Vitamin B2 (mg) 1.4
Vitamin B6 (mg) 1.2
Vitamin B12 (μg) 6.2
Total vitamin C (mg) 23
Vitamin D3 (IU) 290
Vitamin E (mg) 7.5
Pantothenic acid (mg) 2.4
Niacin (mg) 19.6
Folic acid (mg) 0.2
Choline (g) 200
Biotin (μg) 52.8
Inositol (mg) 565
Form Pellet (12.5 mm in diameter), powder (*made-to-order)
Volume 20kg
Package Paper bag (3-layer craft + 1-layer plastic bag)

 

配料 蛋白源 白粉,豆粕,酵母,鱼肝粉
脂肪源 谷类胚芽、大豆油
光纤源 麦麸,脱脂米糠,苜蓿粉
碳水化合物源 小麦粉,玉米,米洛
维生素 维特。A,D3,E,B1,B2,B6,B12,C,烟酸,泛酸,生物素,叶酸,氯化胆碱,肌醇
矿物 碳酸钙,盐,硫酸亚铁,硫酸锰,硫酸钴,碘酸钙
2017年财政分析的平均值
营养成分和卡路里
(100克)
(分析所有生产批次)
水分(%) 8.48
粗蛋白(%) 27.09
粗脂肪(%) 4.69
粗纤维(%) 4.54
粗灰分(%) 7.92
NFE(%)*1 47.28
能源(千卡)*1,2 339.7
硬度(公斤/厘米)2) 24.7
*1根据平均值计算。
*2用粗蛋白(4)、粗脂肪(9)和NFE(4)相乘计算。
矿物(100克)
(对Ca和P.的所有生产批次进行半年一次的分析)
CA(G) 1.54
P(G) 1.32
镁(G) 0.32
k(G) 0.86
锰(镁) 11.33
Fe(Mg) 29.90
Cu(Mg) 0.78
锌(镁) 7.00
NA(G) 0.42
CA/P*1 1.17
Ca/Mg*1 4.83
K/Na*1 2.07
*1根据平均值计算。
维生素(100克)
(半年分析)
视黄醇(IU) 2730
维生素B1(毫克) 1.9
维生素B_2(Mg) 1.4
维生素B6(毫克) 1.2
维生素B1 2(μg) 6.2
总维生素C(毫克) 23
维生素D 3(IU) 290
维生素E(Mg) 7.5
泛酸(Mg) 2.4
烟酸(Mg) 19.6
叶酸(Mg) 0.2
胆碱(G) 200
生物素(μg) 52.8
肌醇(Mg) 565
形式 球团(直径12.5毫米),粉末(*按订单制作)
体积 20公斤
包装 纸袋(3层工艺+1层塑料袋)

上海金畔生物科技有限公司(www.jinpanbio.com)提供生命科学研究领域系列产品,包括生化试剂、诊断试剂、色谱标准品和实验仪器耗材。主营Lumiprobe Cy系列活性荧光染料;修饰性PEG(Laysan bio、NANOCS、Avanti等进口品牌PEG以及定制合成修饰性聚乙二醇、单分散小分量PEG);Sigma、Amresco、TCI、MP bio生化试剂;WAKO日本和光纯药、日本关东化学Kanto试剂、日本三菱、日本柴田科学SIBATA;Megazyme食品分析检测试剂盒、日本共立理化学;Research diets、Harlan饲料、Bio-Serv、日本CLEA Japan品牌的动物饲料;Oxoid、Nissui日水、日本荣研、BD difco、Himedia品牌微生物培养基;免疫诊断试剂包括:Bethyl抗体;Biolegend流式抗体、Abcam、CST、Santa Cruz抗体;Roche、TOYOBO、NEB品牌的酶;中检所、TRC、药典USP、EP、Reagecon标准品;耗材和仪器包括Whatman、日本Advantec滤膜、Millipore品牌的各种滤膜、滤器和柱子填料等、Hampton蛋白结晶试剂耗材、老鼠软管灌胃针、动物毛发记号笔、Labnet、Wheaton瓶子、Bio-Rad伯乐、康宁Corning、Axygen、Falcon 、Eppendorf、Nunc、Nalgene、Nest品牌的培养皿、培养板、离心机、离心管、移液枪及枪头等实验室常用仪器耗材。
上海金畔生物科技有限公司
服务热线:18301939375   QQ:3258089810    3259632176
Email:  info@jinpanbio.com
官网:http://www.jinpanbio.com

Research Diets动物模型饲料份分类

Research Diets动物模型饲料份分类

美国Research Diets公司是一家专业生产实验室动物饲料的顶尖公司,还可以根据客户要求定制特殊饲料,满足客户多方面需求。
Research Diets 公司是一家专业的生产科研实验室动物饲料的大型公司,产品包括高脂、高糖、脂肪肝、酒精肝、动脉硬化、缺铁性贫血饲料、骨质疏松饲料等饲料的世界著名的供应商。
详细信息

美国Research Diets公司是一家专业生产实验室动物饲料的顶尖公司,还可以根据客户要求定制特殊饲料,满足客户多方面需求。自1984年以来,Research Diets已成功开发了10,000种独特的实验室动物模型饲料,覆盖了生命科学的大部分研究领域。
动物模型
Research Diets在表型表达的饮食效应上拥有20年的研发经验,已成功研发了几种模型的饲料,如肥胖症、糖尿病、代谢综合征、动脉粥样硬化、癌症、骨质疏松等。Research Diets的饲料有多种形式:粉末状、颗粒状及液态形式。

适用动物
生产的饲料适用的动物有:大鼠、小鼠、豚鼠、仓鼠、兔子、猪及灵长类动物等。

Cat# 品名 应用 包装
D12450B DIO (LFD) 10 kcal% fat 肥胖、糖尿病 12.5kg
D12451 DIO (HFD) 45 kcal% fat 肥胖、糖尿病 12.5kg
D12492 DIO (VHFD) 60 kcal% fat 肥胖、糖尿病 12.5kg
D10001 AIN-76A 肥胖、糖尿病、 骨质疏松症、高血压、动脉粥样硬化、代谢综合症 12.5kg
D10012G AIN-93G 肥胖、糖尿病、 骨质疏松症、高血压、动脉粥样硬化、代谢综合症 12.5kg
D10012M AIN-93M 肥胖、糖尿病、 骨质疏松症、高血压、动脉粥样硬化、代谢综合症 12.5kg
D12266B Condensed Milk Diet Purified match to C11024 肥胖、糖尿病、高血压 12.5kg
D12489B Low-fat control to D12266B 肥胖、糖尿病、高血压 12.5kg
D12079B RD Western Diet 肥胖、糖尿病、 骨质疏松症、高血压、动脉粥样硬化、代谢综合症 12.5kg
D12330 58 kcal% fat w/corn starch 肥胖、糖尿病 12.5kg
D12328 Control: 11 kcal% fat w/corn starch 肥胖、糖尿病 12.5kg
D12331 58 kcal% fat w/sucrose 肥胖、糖尿病 12.5kg
D12329 Control: 11 kcal% fat w/sucrose 肥胖、糖尿病 12.5kg

Research diets饲料问题答疑

Research diets饲料问题答疑
上海金畔生物代理Research Diets品牌饲料,欢迎客户访问Research Diets品牌官网或者咨询我们获取更多饲料价格等相关信息。
Research Diets 公司是一家专业的生产科研实验室动物饲料的大型公司,产品包括高脂、高糖、脂肪肝、酒精肝、动脉硬化、缺铁性贫血饲料、骨质疏松饲料等饲料的世界著名的供应商。
Q: 1.包装尺寸怎样?
A:Research Diet公司商品的包装尺寸为12.5kg/箱。
基本上Research Diet商品的销售单位为12.5kg。备选的(费用另算)也有
2.5kg >x 5袋的小袋包装。
Q: 2.从订单发行到交货要多长时间?
A: 特供饲料在性质上,大多是收到订单后才开始生产,除了一部分标准商品在国内有库存。此外由于是特殊饲料,Research Diet公司也将库存量压到最小量,几乎都采用JUST IN TIME(准时生产)的方式。关于交货期,在收到订单之后,大约3周后。国内部分产品备有现货。
Q: 3.保存方法如何?
A:多数的Research Diet商品都可以在室温(阴暗场所)保存。在多湿气的冰箱中长期保存,可能会吸收冰箱中的异味。因此请注意保管室提高袋子的密封性。D12492、D12331等超高脂肪饲料的情况下,如果是固态饲料,为了保持其颗粒形状,建议进行冷冻保存。但是,粉末饲料的情况下,由于其组成为脂肪酸,进行冷冻保存的话,会结块,因此取出放入时,注意不要让空气进入,并且收紧袋口,确认其密封性,最好冷藏保存。
Most diets require storage in a cool, dry location. Some diets, especially those with high fat content, are best if kept frozen. Storage requirements are indicated on top of each carton.
Q: 4.品质保存期限是多久?
A:Research Diet饲料的品质保存期限是从生产日开始6个月。送达的商品中会附加如下的标签。从上到下分别为商品名、明细、保存状态、品质保存期限、批号(批号的前6表示生产年月日。如:03_01_15的意思是 2003年1月15日。
例如:
D12492
带有60 kcal% 脂肪的啮齿动物饲料
蓝色
冷冻保存, 有效期: 7月15日
Lot # 03011501
Shelf Life(保质期)
In proper storage conditions OpenSource Diets will last six (6) months. All diets are labeled with an expiration date.
Q: 5.成分、污染物以及重金属分析情况如何?
A:由于是纯化饲料,因此没有进行成分、污染物以及重金属的分析。可以对备选饲料(费用按照实际成本)实施分析。关于费用等详细情况,请进行咨询。
Q: 6.何为“纯化”饲料的脂肪和油脂?
A:经常听到“添加17-20g%以上的脂肪,很难使饲料固体化”,而Research Diet公司通过独有的生产法,做到了60 kcal% fat,质量换算后达到35%。
Q: 7.能否生产和我现在使用的相同饲料?
A:客户如果有自己配方的饲料或者从其他公司生产的饲料,Research Diet公司可以根据客人希望的形状(颗粒、粉末、液体、片剂)生产出与之相同的饲料。此外两周内可以出货。
Q: 8.Research Diet公司饲料的对象动物种类是哪些?
A:Research Diet公司的配方适合大鼠、老鼠、豚鼠,仓鼠、兔子、猫、犬、猴、鸟、豚等所有用途的饲料。
Q: 9.可以公开配方吗?
A:Research Diet公司将含有的全部盐分和维他命成分以及其正确的含量记载在成分表上,可以将该表提交给客户。
Q: 10.保密性如何?
A:Research Diet公司与全球的制药公司、政府机关以及教育机关都有交易,在对客户信息保密方面受到了好评。当然,没有客户事先的同意,有关客户所购入的饲料或者客户正在进行的试验,Research Diet公司绝对不会进行公开。
Q: 11.饲料能否实施消毒?
A:Research Diet公司几乎所有的饲料在封闭环境中可以照射伽马线。纯化饲料的情况下,推荐使用10KGy的射线。希望消毒的客户请向我们咨询。
Q: 12.可以通过怎样的形状进行使用?
A:Research Diet公司几乎所有的饲料都可以生产成为粉末、颗粒、片剂以及液体。 通过Research Diet公司独有的技术,也可以生产出60 kcal%(重量±35%)的高脂肪含量的颗粒状饲料。
Research diets高脂饲料专业代理:

货号 产品名称和描述 研究领域 重量单位
D12450B 精制饲料 DIO饲料 10 Kcal%脂肪(猪油) 肥胖/糖尿病 1箱 12.5 kg
D12451 精制饲料 DIO饲料 45 Kcal%脂肪(猪油) 肥胖/糖尿病 1箱 12.5 kg
D12492 精制饲料 DIO饲料 60 Kcal%脂肪(猪油) 肥胖/糖尿病 1箱 12.5 kg
D12079B 精制饲料 Western饲料 41Kcal%乳脂(牛) 肥胖 1箱 12.5 kg
D10001 精制饲料 AIN-76A标准饲料 标准饲料 1箱 12.5 kg
D10012G 精制饲料 AIN-93G标准饲料 用于训练动物 标准饲料 1箱 12.5 kg
D10012M 精制饲料 AIN-93M标准饲料 用于成熟动物 标准饲料 1箱 12.5 kg
D11724 精制饲料 高碳水化合物型低脂肪饲料(玉米淀粉) 糖尿病 1箱 12.5 kg
D11725 精制饲料 高碳水化合物型低脂肪饲料(高蔗糖) 糖尿病 1箱 12.5 kg
D12331 精制饲料 Surwit’s饲料 58Kcal%脂肪(椰子油、玉米淀粉) 糖尿病 1箱 12.5 kg
D12336 精制饲料 心血管疾病的饲料 高胆固醇 循环器官 1箱 12.5 kg

Research Diets A02082002B MCD饲料-非酒精性脂肪肝模型饲料

Research Diets A02082002B MCD饲料-非酒精性脂肪肝模型饲料
英文名称:methionine-choline deficient diet, MCD
产地/品牌:Research Diets
产品类别:非酒精性脂肪肝模型饲料
Research Diets 公司是一家专业的生产科研实验室动物饲料的大型公司,产品包括高脂、高糖、脂肪肝、酒精肝、动脉硬化、缺铁性贫血饲料、骨质疏松饲料等饲料的世界著名的供应商。
非酒精性脂肪性肝病(NAFLD)是全世界范围内最普遍的一种肝脏疾病和肝功能检测异常的最常见诱因,包含一系列的疾病状态。从最初单纯的脂肪变性(肝硬化)发展至病理性的非酒精性肝炎(Nonalcoholic steatohepatitis, NASH),进一步引起肝纤维化,甚至导致肝硬化、肝功能衰竭和肝癌等终末期肝病。NASH的发病常常与肥胖症、胰岛素抵抗、线粒体功能异常、II型糖尿病等相关。作为严重肝病发生的必经阶段,对NASH发病机制的认识和治疗极具重要性。
目前对NASH发病机制和评估治疗成效的研究主要以合适的动物模型为平台。营养诱发动物模型(食物喂养法)是NASH动物模型建立最常用的方法。其中MCD(methionine-cholinedeficient diet)和HFD(high-fat diet)为诱导NASH的两种常见饲料,研究者可根据各个方法的成模特征、周期、动物类型等选择适宜的方法。
专题一 NASH动物模型(MCD法)
简 介
蛋氨酸/胆碱缺乏饲料(methionine-choline deficient diet, MCD)是最经典的建立NASH动物模型的方法,已经具有40多年的应用历史。一般选用啮齿类动物。是研究NASH疾病相关的炎症、氧化应激、线粒体损伤、肝纤维化的最佳建模方法。
Mpbio公司提供两种类型的MCD动物饲料,分别是粉末状(powder)和颗粒状(pellet)。另外还提供MCD对照饲料,与普通MCD饲料配方相同,只是在减少等量蔗糖的基础上,增加2g/kg 氯化胆碱和3 g/kg DL-蛋氨酸。
Research Diets A02082002B MCD饲料-非酒精性脂肪肝模型饲料
CD / MCD 特殊飼料:
Research Diets 货号  A02082002B,  methionine and choline-deficient diet (MCD)  ;
Research Diets 货号  A02082003B(MCD   contronl diets); 对照组

Harlan Teklad动物饲料目录以及Harlan饲料价格

Harlan Teklad动物饲料目录以及Harlan饲料价格
Harlan Teklad动物饲料
Harlan代理
欢迎新老客户访问Harlan官网或者咨询中国代理商上海金畔生物获取更多详细资料。
Harlan Teklad动物饲料目录以及Harlan饲料价格

TD.94045 AIN-93G Purified Diet AIN-93G纯化饮食
TD.94048 AIN-93M Purified Diet AIN-93M纯化饮食
TD.94096 version of AIN-76A suitable for irradiation (vitamin levels are increased) 适用于辐射的AIN-76A型(维生素水平增加)
TD.97184 version of AIN-93G suitable for irradiation (vitamin levels are increased) 适用于辐照的AIN-93G版本(维生素水平增加)
TD.00102 version of AIN-93M suitable for irradiation (vitamin levels are increased) 适用于辐照的AIN-93M版本(增加维生素水平)
TD.95092 modification of AIN-93G where soybean oil is replaced with corn oil. 用玉米油代替豆油的AIN-93G的改性。
TD.06414 Adjusted Calories Diet (60/Fat) 调整后的卡路里饮食(60 /脂肪)
TD.06415 Adjusted Calories Diet (45/Fat) 调整后的卡路里饮食(45 /脂肪)
TD.03584 35% Lard Diet (Adj., No C) 35%猪油饮食(调整,否C)
TD.93075 Adjusted Calories Diet (55/fat) 调整后的卡路里饮食(55 /脂肪)
TD.95217 Adjusted Fat Diet 调整脂肪饮食
TD.96132 Adjusted Fat Diet 调整脂肪饮食
TD.88137 Adjusted Kcal Diet (42% from fat 调整后的Kcal饮食(42%来自脂肪
TD.08811 45% Kcal Fat Diet (21% MF, 2% SBO) 45%Kcal脂肪饮食(21%MF,2%SBO)
TD.06416 Adjusted Calories Diet (10/Fat) (a possible control for TD.06415 & TD.06414 listed above) 调整后的卡路里饮食(10 /脂肪)(上面列出的TD.06415和TD.06414的可能控制)
TD.08810 Low Glycemic Control Diet 低血糖控制饮食
TD.96355 Ketogenic Diet 生酮饮食
TD.84224 Essential Fatty Acid Deficient Diet 必需脂肪酸缺乏饮食
TD.88137 Adjusted Calories Diet (42% from fat) 调整后的卡路里饮食(42%来自脂肪)
TD.88051 Cocoa Butter and Purina Chow Diet 可可脂和Purina Chow饮食
TD.90221 Cocoa Butter Diet with 75% Purina Mouse (5015) 含75%Purina小鼠的可可脂饮食(5015)
TD.94059 5015, Cocoa Butter, Chol., etc. (excludes cholate) 5015,可可脂,Chol。等(不包括胆酸盐)
TD.02028 Atherogenic Rodent Diet (1.25% Chol. & 0.5% Cholic Acid) 动脉粥样硬化啮齿动物饮食(1.25%Chol。和0.5%胆酸)
TD.01383 2018 + 2% Cholesterol 2018 + 2%胆固醇
TD.86143 Vitamin A Deficient Diet 维生素A缺乏饮食
TD.89123 Vitamin D Deficient Diet 维生素D缺乏饮食
TD.88163 Vitamin E Deficient Diet 维生素E缺乏饮食
TD.95247 Folic Acid Deficient Diet 叶酸缺乏饮食
TD.80396 Iron Deficient Diet 缺铁饮食
TD.85419 Zinc Deficient Diet 锌缺乏饮食
TD.88239 Potassium Deficient Diet 缺钾饮食
TD.95027 Low Calcium Diet (0.4% P) 低钙饮食(0.4%P)
TD.96348 Diet (20% Lactose, 2% Ca, 1.25% P) 饮食(20%乳糖,2%Ca,1.25%P)
TD.92163 Selenium Deficient Diet 硒缺乏饮食
TD.95125 Iodine Deficient (0.15% PTU) 碘缺乏(0.15%PTU)
TD.93328 Protein Free Diet 无蛋白质饮食
TD.90016 6% Protein Diet 6%蛋白质饮食
TD.91352 20% Protein Diet 20%蛋白质饮食
TD.90018 40% Protein Diet 40%蛋白质饮食
TD.89247 60% Fructose Diet 60%果糖饮食
TD.86489 Diet with Adjusted Sucrose/Cornstarch 调整蔗糖/玉米淀粉的饮食
TD.96348 Diet (20% Lactose, 2% Ca, 1.25% P) 饮食(20%乳糖,2%Ca,1.25%P)
TD.98090 70% Carbohydrate Diet 70%碳水化合物饮食
TD.96355 Ketogenic Diet (almost no carbohydrate) 生酮饮食(几乎不含碳水化合物)
TD.99366 Amino Acid Diet 氨基酸饮食
TD.90262 Methionine & Choline Deficient Diet 蛋氨酸和胆碱缺乏饮食
TD.00434 Folic Acid Deficient Diet 叶酸缺乏饮食
TD.99386 No Lysine AA Diet 没有赖氨酸AA饮食
TD.90228 Sodium Deficient Diet 钠缺乏饮食
TD.96208 0.49% NaCl Diet 0.49%NaCl饮食
TD.90229 1% NaCl Diet 1%NaCl饮食
TD.92034 4% NaCl Diet 4%NaCl饮食
TD.92012 8% NaCl Diet 8%NaCl饮食
TD.01306 Rodent Diet (2018 + 625 doxycycline) 啮齿动物饮食(2018 + 625强力霉素)
TD.98186 Rodent Diet (7012 + 200 doxycycline) 啮齿动物饮食(7012 + 200强力霉素)
TD.92033 Swine Diet (15% Lard, 1.2% Cholesterol) 猪日粮(15%猪油,1.2%胆固醇)
TD.92052 Swine Diet (15% Lard, 1.5% Cholesterol) 猪日粮(15%猪油,1.5%胆固醇)
TD.93296 Swine Diet (15% Lard, 2% Cholesterol) 猪日粮(15%猪油,2%胆固醇)
CA.40060 Teklad Vitamin Mix Teklad维生素混合物
CA.40077 AIN-76A Vitamin Mix AIN-76A维生素混合物
TD.94047 AIN-93 Vitamin Mix AIN-93维生素混合物
CA.170915 AIN-76 Mineral Mix AIN-76矿物质混合物
TD.94046 AIN-93G Mineral Mix AIN-93G矿物质混合物
TD.94049 AIN-93M Mineral Mix AIN-93M矿物质混合物
TD.79055 Calcium & Phosphorus Deficient Mineral Mixed based on AIN-76 基于AIN-76的钙磷缺乏矿物混合物
TD.98057 Calcium & Phosphorus Deficient Mineral Mixed based on AIN-93 基于AIN-93的钙磷缺乏矿物混合物

Harlan 动脉粥样硬化(胆固醇、脂肪、胆酸盐) 饲料Atherogenic

Harlan 动脉粥样硬化(胆固醇、脂肪、胆酸盐) 饲料Atherogenic
Harlan Teklad动物饲料
Harlan代理
欢迎新老客户访问Harlan官网或者咨询中国代理商上海金畔生物获取更多详细资料。
Harlan 动脉粥样硬化(胆固醇、脂肪、胆酸盐) 饲料Atherogenic
Atherogenic

Research use Key dietary features Examples
“Western” purified atherogenic diet
Accelerated hypercholesterolemia and plaque formation in genetically modified models such as Apoe and Ldlr deficient mice.
Used for diet induced obesity in a variety of rodent models.
High fat diet (20 – 23% by weight; 40 – 45% kcal from fat)
Saturated fatty acids (SFA >60% of total fatty acids)
Milkfat/butterfat
Sucrose (34% by weight)
Cholesterol (0.2% total)
TD.88137
TD.10885
“Western” purified atherogenic diet with added cholesterol and cholate source*
Induce hypercholesterolemia and mild atherosclerosis (foam cells, fatty streaks) in primarily wild type mice and rats.
Will not promote obesity.
High fat diet (15 – 20% by weight; 34 – 45% kcal from fat)
Saturated fatty acids (SFA >55% of total fatty acids)
Milkfat/butterfat, cocoa butter
Sucrose (30-50% by weight)
Cholesterol (1 – 1.25%)
Cholate Source (0.5%)*
TD.02028
TD.09237
Hybrid high fat diets with added cholesterol and cholate source*
Induce hypercholesterolemia and mild atherosclerosis (foam cells, fatty streaks) in primarily wild type mice and rats.
Will not promote obesity.
Also used for lithogenic (gallstone) rodent studies.
75% rodent breeder diet; 25% purified ingredients
High fat (~15% by weight; 37% kcal from fat)
Saturated fatty acids (SFA >45% of total fatty acids)
Cholesterol (1.25%)
Cholate source (0.5%)*
TD.88051
TD.90221
Standard diets with added cholesterol
Induce hypercholesterolemia in genetically modified and wild type models without promoting obesity. Standard, grain-based rodent diet
Minimal/moderate phytoestrogen diets recommended
Cholesterol (1 – 4%)
TD.120097
TD.07841
TD.01383

*Sodium cholate or cholic acid aid cholesterol and fat absorption and reduce cholesterol disposal via bile acid synthesis. However, if including a cholate source is not desired for your research, diets without cholate are available.
*Sodium cholate or cholic acid aid cholesterol and fat absorption and reduce cholesterol disposal via bile acid synthesis.However, if including a cholate source is not desired for your research, diets without cholate are available.

在实验动物模型中,饮食是诱导或加速动脉粥样硬化的有用工具。用于诱发啮齿类动物动脉粥样硬化的主要饮食特征因研究模型、所需终点和喂养时间的不同而不同。尽管动脉粥样硬化饮食的配方在不断发展,但文献中详细描述的备选方案概述如下。有关每个饮食选项和文献参考的更多信息,请参见节目表后面的可扩展选项卡。
研究用途 主要饮食特征 实例
“西方”纯正致动脉粥样硬化饮食
加速高胆固醇血症和斑块形成的转基因模型,如APOE和Ldlr缺乏的小鼠。
用于饮食诱导肥胖的各种啮齿动物模型。
  • 高脂饮食(按体重计算占20-23%;脂肪占40-45%)
  • 饱和脂肪酸(SFA>总脂肪酸的60%)
  • 乳脂/乳脂
  • 蔗糖(按重量计占34%)
  • 胆固醇(总数0.2%)
TD.88137
TD.10885
添加胆固醇和胆酸来源的“西方”纯动脉粥样硬化饮食*
在野生型小鼠和大鼠中诱导高胆固醇血症和轻度动脉粥样硬化(泡沫细胞、脂肪条纹)。
不会助长肥胖。
  • 高脂饮食(体重15-20%;脂肪34-45千卡)
  • 饱和脂肪酸(SFA>总脂肪酸的55%)
  • 乳脂/黄油、可可脂
  • 蔗糖(重量占30%-50%)
  • 胆固醇(1-1.25%)
  • 巧克力来源(0.5%)*
TD.02028
TD.09237
添加胆固醇和胆酸盐的混合高脂饮食*
在野生型小鼠和大鼠中诱导高胆固醇血症和轻度动脉粥样硬化(泡沫细胞、脂肪条纹)。
不会助长肥胖。
也用于造石(胆石)啮齿动物的研究。
  • 75%的啮齿动物饲养员;25%的纯化成分
  • 高脂肪(体重约15%;脂肪37%千卡)
  • 饱和脂肪酸(SFA>总脂肪酸的45%)
  • 胆固醇(1.25%)
  • 巧克力源(0.5%)*
TD.88051
TD.90221
添加胆固醇的标准饮食
在转基因和野生型模型中诱导高胆固醇血症而不促进肥胖。
  • 标准的、以谷物为基础的啮齿动物饮食
  • 最小/中度植物雌激素饮食建议
  • 胆固醇(1-4%)
TD.120097
TD.07841
TD.01383

*胆酸钠或胆酸有助胆固醇和脂肪的吸收,并可透过胆汁酸合成减少胆固醇的排出。然而,如果你的研究不想包括胆酸盐的来源,没有胆酸盐的饮食是可用的。

“Western” purified atherogenic diet
“Western” style diets are fed to genetically-modified cardiovascular models, such as Apoe and Ldlr deficient mice, to accelerate and enhance hypercholesterolemia and plaque formation and to elicit phenotypes commonly associated with metabolic syndrome.Within the atherogenic literature, a “Western” diet typically is described as a purified rodent diet with 20-23% milkfat/butterfat, 0.2% total cholesterol, and 34% sucrose by weight.TD.88137is an example of a “Western” style diet that was originally designed to characterize and enhance atherosclerosis development in a newly generated Apoe-deficient mouse model.Contact us for more information about “Western” style diets, modifications, or possible control diets.
Examples:
TD.88137Adjusted calories diet (42% from fat, 0.2% total cholesterol)
TD.1088545% fat Kcal diet (0.2% total cholesterol)
Research use:
Accelerated hypercholesterolemia and plaque formation in genetically-modified models, such as Apoe and Ldlr deficient mice.
Used for diet-induced obesity in a variety of rodent models.
Key dietary features:
High Fat Diet (20-23% by weight; 40 – 45% kcal from fat)
Saturated fatty acids (SFA >60% of total fatty acids)
Milkfat/butterfat
Sucrose (34% by weight)
Cholesterol (0.2% total)
References:
1.Febbraio, M., et al., Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice.J Clin Invest, 2000.105(8): p.1049-56.
2.Huszar, D., et al., Increased LDL cholesterol and atherosclerosis in LDL receptor-deficient mice with attenuated expression of scavenger receptor B1.Arterioscler Thromb Vasc Biol, 2000.20(4): p.1068-73.
3.Nakashima, Y., et al., ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree.Arterioscler Thromb, 1994.14(1): p.133-40.
4.Nakashima, Y., et al., Upregulation of VCAM-1 and ICAM-1 at atherosclerosis-prone sites on the endothelium in the ApoE-deficient mouse.Arterioscler Thromb Vasc Biol, 1998.18(5): p.842-51.
5.Plump, A.S., et al., Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells.Cell, 1992.71(2): p.343-53.
6.Towler, D.A., et al., Diet-induced diabetes activates an osteogenic gene regulatory program in the aortas of low density lipoprotein receptor-deficient mice.J Biol Chem, 1998.273(46): p.30427-34.
7,Tsuchiya, K., et al., FoxOs integrate pleiotropic actions of insulin in vascular endothelium to protect mice from atherosclerosis.Cell Metab, 2012.15(3): p.372-81.
“Western” purified atherogenic diet with added cholesterol and cholate source*
Wild type mice and rats generally are resistant to atherosclerosis, requiring more extreme dietary manipulation to modify lipoprotein profiles and develop mild atherosclerosis (foam cells, fatty streaks).Modern formulations are made completely of purified ingredients because this more refined approach has been reported to decrease the incidence of gallstones and liver damage associated with less refined and more traditional dietary approaches.To induce mild atherosclerosis in wild type animals, the “Western” purified diet can be modified to increase cholesterol (1-1.25%) and add a bile salt such as sodium cholate or cholic acid.Contact us for more information, modifications, or possible control diets.
Examples of purified high fat diets with added cholesterol and cholate source*:
TD.0202821% milkfat (1.25% cholesterol, 0.5% cholic acid)
TD.0923715% milkfat diet (1% cholesterol, 0.5% sodium cholate)
Examples of purified high fat diets with added cholesterol (without cholate source):
TD.9612121% milkfat (1.25% cholesterol)
Research Use:
Induce hypercholesterolemia and mild atherosclerosis (foam cells, fatty streaks) primarily in wild type mice and rats.
Will not promote obesity.
Key dietary features:
High fat diet (15-20% by weight; 34 – 45% kcal from fat)
Saturated fatty acids (SFA >55% of total fatty acids)
Milkfat/butterfat, cocoa butter
Sucrose (30-50% by weight)
Cholesterol (1 – 1.25%)
Cholate source (0.5%)*
References:
1.Bernal, C., et al., Lipid biomarkers and metabolic effects of lycopene from tomato juice on liver of rats with induced hepatic steatosis.J Nutr Biochem, 2013.24(11): p.1870-81.
2.Gao, Q., et al., Atherogenic diets exacerbate colitis in mice deficient in glutathione peroxidase.Inflamm Bowel Dis, 2010.16(12): p.2043-54.
3.Lichtman, A.H., et al., Hyperlipidemia and atherosclerotic lesion development in LDL receptor-deficient mice fed defined semipurified diets with and without cholate.Arterioscler Thromb Vasc Biol, 1999.19(8): p.1938-44.
4.Marcondes, M.C., et al., Effects of chronic mental stress and atherogenic diet on the immune inflammatory environment in mouse aorta.Brain Behav Immun, 2011.25(8): p.1649-57.
5.Nishina, P.M., et al., Effects of dietary fats from animal and plant sources on diet-induced fatty streak lesions in C57BL/6J mice.J Lipid Res, 1993.34(8): p.1413-22.
6.Nishina, P.M., et al., Atherosclerosis and plasma and liver lipids in nine inbred strains of mice.Lipids, 1993.28(7): p.599-605.
7.Yue, P., et al., Enhanced hepatic apoA-I secretion and peripheral efflux of cholesterol and phospholipid in CD36 null mice.PLoS One, 2010.5(3): p.e9906.
8.Nishina, P.M., J. Verstuyft, and B. Paigen, Synthetic low and high fat diets for the study of atherosclerosis in the mouse.J Lipid Res, 1990.31(5): p.859-69.
*Sodium cholate or cholic acid aid cholesterol and fat absorption and reduce cholesterol disposal via bile acid synthesis.However, if including a cholate source is not desired for your research, diets without cholate are available.SeeTD.96121for a purified diet andTD.94059for a hybrid diet.Contact us for additional options.
Hybrid high fat diets with added cholesterol and cholate source*
Beverly Paigen and colleagues first characterized atherosclerosis development in C57BL/6 mice by feeding a hybrid atherogenic diet.The hybrid diet was created by mixing a natural ingredient mouse diet in a 3:1 ratio with a concentrated purified diet (containing 5% cholesterol and 2% sodium cholate; referred to as Thomas-Hartroft diet).The resulting mixture recreated inTD.88051/TD.90221(same formula) contains ~15.8% fat, 1.25% cholesterol, and 0.5% sodium cholate.This group later compared the hybrid atherogenic diet approach to the more modern “western” purified atherogenic diet with added cholesterol and cholate and found that the hybrid atherogenic diet induced more gallstones and liver damage.Hybrid diets contain a variety of unrefined ingredients that may modify lipid metabolism and atherogenesis and do not allow for precise control of ingredients and nutrients for the study of chronic diseases.Although more refined diets have been developed, hybrid atherogenic diets are still popular for inducing mild atherosclerosis and gallstones in wild type mice and rats.Contact us for more information, modifications, or possible control diets.
Examples of hybrid high-fat diets with added cholesterol and cholate source*:
TD.88051andTD.90221(same formula) are Teklad product codes for hybrid atherogenic diets
Example of hybrid high-fat diet with added cholesterol (without cholate source):
TD.94059
Research Use:
Induce hypercholesterolemia and mild atherosclerosis (foam cells, fatty streaks) primarily in wild type mice and rats.
Will not promote obesity.
Also used for lithogenic (gallstone) rodent studies.
Key dietary features:
75% rodent breeder diet; 25% purified ingredients
High fat (~15% by weight; 37% kcal from fat)
Saturated fatty acids (SFA >45% of total fatty acids)
Cholesterol (1.25%)
Cholate source (0.5%)*
References:
1.Nishina, P.M., J. Verstuyft, and B. Paigen, Synthetic low and high fat diets for the study of atherosclerosis in the mouse.J Lipid Res, 1990.31(5): p.859-69.
2.Clee, S.M., et al., Plasma and vessel wall lipoprotein lipase have different roles in atherosclerosis.J Lipid Res, 2000.41(4): p.521-31.
3.George, J., et al., Enhanced fatty streak formation in C57BL/6J mice by immunization with heat shock protein-65.Arterioscler Thromb Vasc Biol, 1999.19(3): p.505-10.
4.Miyake, J.H., et al., Transgenic expression of cholesterol-7-alpha-hydroxylase prevents atherosclerosis in C57BL/6J mice.Arterioscler Thromb Vasc Biol, 2002.22(1): p.121-6.
5.Paigen, B., et al., Quantitative assessment of atherosclerotic lesions in mice.Atherosclerosis, 1987.68(3): p.231-40.
6.Schreyer, S.A., D.L. Wilson, and R.C. LeBoeuf, C57BL/6 mice fed high fat diets as models for diabetes-accelerated atherosclerosis.Atherosclerosis, 1998.136(1): p.17-24.
7.Vergnes, L., et al., Cholesterol and cholate components of an atherogenic diet induce distinct stages of hepatic inflammatory gene expression.J Biol Chem, 2003.278(44): p.42774-84.
*Sodium cholate or cholic acid aid cholesterol and fat absorption and reduce cholesterol disposal via bile acid synthesis.However, if including a cholate source is not desired for your research, diets without cholate are available.SeeTD.96121for a purified diet andTD.94059for a hybrid diet.Contact us for additional options.
Standard diets with added cholesterol
Standard, natural ingredient diets with cholesterol added are fed to induce hypercholesterolemia.Various levels of cholesterol, fat, and/or bile salts can be added to one of the numerous standard rodent diets stocked by Envigo Teklad.For many applications, adding these components to Envigo’s minimal-to-moderate phytoestrogen global rodent diets is recommended.Our minimal phytoestrogen global rodent diets are soybean meal free, limiting the effect of phytoestrogens on your research outcomes.Soybean meal, a common dietary source of phytoestrogens, has been shown to decrease aortic fatty streak development and modify plasma cholesterol, which may reduce the risk of developing atherosclerosis.Limiting dietary soybean meal may reduce confounding variables within your dietary-induced atherosclerosis model.Contact a nutritionist to discuss additional diet options.
Examples of minimal and moderate phytoestrogen rodent diets with added cholesterol:
TD.1200971% cholesterol diet (2020 – minimal phytoestrogens)
TD.078412% cholesterol diet (2016 – minimal phytoestrogens)
TD.013832% cholesterol (2018 – Moderate phytoestrogens)
Research use:
Induce hypercholesterolemia in genetically-modified and wild type models without promoting obesity.
Key dietary features:
Standard, grain-based rodent diet
Minimal/moderate phytoestrogen diets recommended
Cholesterol (1 – 4%)
References:
1.Belch, J.J., et al., Longitudinal assessment of endothelial function in the microvasculature of mice in-vivo.Microvasc Res, 2013.85: p.86-92.
2.Hartvigsen, K., et al., A diet-induced hypercholesterolemic murine model to study atherogenesis without obesity and metabolic syndrome.Arterioscler Thromb Vasc Biol, 2007.27(4): p.878-85.
Diets for additional animal models of atherosclerosis
Rabbits, hamsters, and swine are common models of atherosclerosis.Contact a nutritionist for information and formula examples.Seerabbit, swine and other speciesfor information and formula examples.
“西方”纯正致动脉粥样硬化饮食

“西式”饮食被喂给基因修饰的心血管模型,如APOE和Ldlr缺乏的小鼠,以加速和促进高胆固醇血症和斑块形成,并引出通常与代谢综合征相关的表型。在动脉粥样硬化的文献中,“西方”饮食通常被描述为含有20-23%乳脂/蝴蝶脂肪、0.2%总胆固醇和34%蔗糖的纯啮齿动物饮食。TD.88137这是一种“西式”饮食的例子,最初的目的是在一种新生成的APOE缺陷小鼠模型中描述和促进动脉粥样硬化的发展。联系我们,以获得更多关于“西方”风格的饮食,修改,或可能的控制饮食。
例子:

  • TD.88137调整卡路里饮食(42%来自脂肪,0.2%总胆固醇)
  • TD.1088545%脂肪KCAL饮食(总胆固醇0.2%)

研究用途:
加速高胆固醇血症和斑块形成的转基因模型,如APOE和Ldlr缺乏的小鼠。
用于饮食诱导肥胖的各种啮齿动物模型。
主要饮食特征:

  • 高脂肪饮食(按体重计算占20-23%;脂肪占40-45%)
  • 饱和脂肪酸(SFA>总脂肪酸的60%)
  • 乳脂/乳脂
  • 蔗糖(按重量计占34%)
  • 胆固醇(总数0.2%)
野生型小鼠和大鼠一般对动脉粥样硬化有抵抗力,需要更极端的饮食操作来改变脂蛋白谱,形成轻度动脉粥样硬化(泡沫细胞、脂肪条纹)。现代配方完全是由纯化成分制成的,因为据报道,这种更精细的方法可以减少较少精制和较传统饮食方法引起的胆结石和肝脏损害的发生率。为了在野生型动物中诱导轻度动脉粥样硬化,可对“西方”纯化饲料进行改良,以提高胆固醇(1-1.25%),并添加胆酸钠或胆酸等胆盐。联系我们获得更多的信息,修改,或可能的控制饮食。
添加胆固醇和胆酸盐来源的纯化高脂饮食的例子*:

  • TD.0202821%乳脂(1.25%胆固醇,0.5%胆酸)
  • TD.0923715%乳脂饮食(1%胆固醇,0.5%胆酸钠)

添加胆固醇的纯化高脂饮食的例子(没有胆酸来源):

  • TD.9612121%乳脂(1.25%胆固醇)

研究用途:
主要在野生型小鼠和大鼠诱发高胆固醇血症和轻度动脉粥样硬化(泡沫细胞、脂肪条纹)。
不会助长肥胖。
主要饮食特征:

  • 高脂饮食(体重15-20%;脂肪34-45千卡)
  • 饱和脂肪酸(SFA>总脂肪酸的55%)
  • 乳脂/黄油、可可脂
  • 蔗糖(重量占30%-50%)
  • 胆固醇(1-1.25%)
  • 巧克力源(0.5%)*

*胆酸钠或胆酸有助胆固醇和脂肪的吸收,并可透过胆汁酸合成减少胆固醇的排出。然而,如果你的研究不想包括胆酸盐的来源,没有胆酸盐的饮食是可用的。看见TD.96121为了纯正的饮食TD.94059混合饮食。请与我们联系,了解其他选项。

贝弗利·派根和他的同事首先通过喂养一种混合性动脉粥样硬化饮食来描述C57BL/6小鼠动脉粥样硬化的发展。这种混合饲料是通过将一种天然成分的老鼠饲料按3:1的比例与浓缩的纯化饲料(含5%胆固醇和2%胆酸钠;称为Thoms-Hartroft饮食)混合而成的。产生的混合物在TD.88051/TD.90221(同配方)含有~15.8%脂肪、1.25%胆固醇和0.5%胆酸钠。这组人后来将混合动脉粥样硬化饮食方法与更现代的“西方”纯化动脉粥样硬化饮食方法进行了比较,并添加了胆固醇和胆酸盐,发现混合动脉粥样硬化饮食会导致更多的胆结石和肝脏损伤。混合饮食含有多种未精制的成分,这些成分可能会改变血脂代谢和动脉粥样硬化的发生,并且不允许对成分和营养物进行精确控制,以用于慢性病的研究。虽然已经开发出了更精细的饮食,但混合动脉粥样硬化饮食仍然是野生型小鼠和大鼠诱发轻度动脉粥样硬化和胆结石的流行食品。联系我们获得更多的信息,修改,或可能的控制饮食。
添加胆固醇和胆酸盐的混合高脂饮食实例*:

  • TD.88051和TD.90221(相同的配方)是特克拉德混合动脉粥样硬化饮食的产品代码。

添加胆固醇的混合高脂饮食的例子(没有胆酸来源):

  • TD.94059

研究用途:
主要在野生型小鼠和大鼠诱发高胆固醇血症和轻度动脉粥样硬化(泡沫细胞、脂肪条纹)。
不会助长肥胖。
也用于造石(胆石)啮齿动物的研究。
主要饮食特征:

  • 75%的啮齿动物饲养员;25%的纯化成分
  • 高脂肪(体重约15%;脂肪37%千卡)
  • 饱和脂肪酸(SFA>总脂肪酸的45%)
  • 胆固醇(1.25%)
  • 巧克力源(0.5%)*

*胆酸钠或胆酸有助胆固醇和脂肪的吸收,并可透过胆汁酸合成减少胆固醇的排出。然而,如果你的研究不想包括胆酸盐的来源,没有胆酸盐的饮食是可用的。看见TD.96121为了纯正的饮食TD.94059混合饮食。请与我们联系,了解其他选项。

标准的,添加胆固醇的天然成分饮食是用来诱导高胆固醇血症的。不同水平的胆固醇,脂肪和/或胆汁酸盐可以添加到众多的标准啮齿动物饮食之一,由EnvigoTeclad。在许多应用中,建议将这些成分添加到Envigo的最小到中等植物雌激素的全球啮齿动物饮食中。我们最小的植物雌激素全球啮齿动物饮食是不含豆粕的,限制了植物雌激素对你的研究结果的影响。豆粕是一种常见的植物雌激素来源,它可以减少主动脉脂肪条纹的发育,改善血浆胆固醇,从而降低动脉粥样硬化的风险。限制饮食豆粕可能会减少饮食诱导动脉粥样硬化模型中的混杂变量。联系营养学家讨论其他饮食选择。
添加胆固醇的最小和中度植物雌激素啮齿动物饮食的例子:

  • TD.120097  1%胆固醇饮食(2020年-最小植物雌激素)
  • TD.07841  2%胆固醇饮食(2016年-最小植物雌激素)
  • TD.01383  2%胆固醇(2018年-中度植物雌激素)

研究用途:
在转基因和野生型模型中诱导高胆固醇血症而不促进肥胖。
主要饮食特征:

  • 标准的、以谷物为基础的啮齿动物饮食
  • 最小/中度植物雌激素饮食建议
  • 胆固醇(1-4%)
兔子、仓鼠和猪是动脉粥样硬化的常见模型。请与营养师联系,了解有关信息和公式示例。看见兔子、猪和其他物种有关信息和公式示例。

Harlan TD.95027低钙饲料(0.4%P)

Harlan TD.95027低钙饲料(0.4%P)
Harlan货号:TD.95027
英文名称:Low Calcium Diet (0.4% P)
Harlan Teklad动物饲料
Harlan代理
欢迎新老客户访问Harlan官网或者咨询中国代理商上海金畔生物获取更多详细资料。
Formula                                                                     g/Kg
Casein                                                                    200.0
Cystine                                                                     3.0
Sucrose                                                            342.188
Corn Starch                                                         320.0
Soybean Oil                                                          60.0
Cellulose                                                              40.0
Mineral Mix, Ca-P Deficient (79055)                    13.37
Potassium Phosphate, monobasic                     11.43
Vitamin Mix, Teklad (40060)                                10.0
Ethoxyquin, antioxidant                                       0.012
Key Features
+ Purified Diet
+ Calcium
+ Phosphorus
Key Planning Information
+ Products are made fresh to order
+Store product at 4°C or lower
+Use within 6 months (applicable to most diets)
+Box labeled with product name, manufacturing date, and lot number
+ Replace diet at minimum once per week More frequent replacement may be advised
+ Lead time:
· 2 weeks non-irradiated
· 4 weeks irradiated
上海金畔生物科技有限公司(www.jinpanbio.com)提供生命科学研究领域系列产品,包括生化试剂、诊断试剂、色谱标准品和实验仪器耗材。主营Lumiprobe Cy系列活性荧光染料;修饰性PEG(Laysan bio、NANOCS、Avanti等进口品牌PEG以及定制合成修饰性聚乙二醇、单分散小分量PEG);Sigma、Amresco、TCI、MP bio生化试剂;WAKO日本和光纯药、日本关东化学Kanto试剂、日本三菱、日本柴田科学SIBATA;Megazyme食品分析检测试剂盒、日本共立理化学;Research diets、Harlan饲料、Bio-Serv、日本CLEA Japan品牌的动物饲料;Oxoid、Nissui日水、日本荣研、BD difco、Himedia品牌微生物培养基;免疫诊断试剂包括:Bethyl抗体;Biolegend流式抗体、Abcam、CST、Santa Cruz抗体;Roche、TOYOBO、NEB品牌的酶;中检所、TRC、药典USP、EP、Reagecon标准品;耗材和仪器包括Whatman、日本Advantec滤膜、Millipore品牌的各种滤膜、滤器和柱子填料等、Hampton蛋白结晶试剂耗材、老鼠软管灌胃针、动物毛发记号笔、Labnet、Wheaton瓶子、Bio-Rad伯乐、康宁Corning、Axygen、Falcon 、Eppendorf、Nunc、Nalgene、Nest品牌的培养皿、培养板、离心机、离心管、移液枪及枪头等实验室常用仪器耗材。
上海金畔生物科技有限公司
服务热线:18301939375   QQ:3258089810    3259632176
Email:  info@jinpanbio.com
官网:http://www.jinpanbio.com

Harlan TD.81062 说明书 Iron deficient mineral mix based on AIN-76A

Harlan TD.81062 说明书 Iron deficient mineral mix based on AIN-76A
Harlan Teklad动物饲料
Harlan代理
欢迎新老客户访问Harlan官网或者咨询中国代理商上海金畔生物获取更多详细资料。
Formula
Calcium Phosphate, dibasic   500.0
Sodium Chloride   74.0
Potassium Citrate, monohydrate   220.0
Potassium Sulfate   52.0
Magnesium Oxide   24.0
Manganous Carbonate   3.5
Zinc Carbonate   1.6
Cupric Carbonate   0.3
Potassium Iodate    0.01
Sodium Selenite, pentahydrate   0.01
Chromium Potassium Sulfate, dodecahydrate    0.55
Sucrose, fine ground    124.03
Key Features
+ Mineral Mix
+ Modified From AIN-76
+ Iron Deficient
+ Rodent
Key Planning Information
+ Products are made fresh to order
+ Lead time 2 weeks
+Store in cool, dry conditions
+ Use within 12 months (applicable to most mixes)
+ Box labeled with product name,
manufacturing date, and lot number
Product Specific Information
+ Powder
+ Minimum order 500 grams
Footnote
This modification of the AIN-76 mineral mix (170915) uses a reagent
grade/pretested CaHPO4 to help reduce the inherent background iron
contributed from this compound. The mineral mix itself is tested for iron
content prior to use.
Options (fees will apply)
+ Rush order (pending availability)
+ Vacuum packaging (1 and 2 Kg)
CA.170481 AIN-76A Purified Diet AIN-76A 纯化饲料 50kg
TD.94045 AIN-93G Purified Diet AIN-93G 纯化饲料 50kg
TD.94048 AIN-93M Purified Diet AIN-93M 纯化饲料 50kg
TD.94096 version of AIN-76A suitable for irradiation (vitamin levels are increased) 适合辐照的AIN-76A 饲料 维生素含量增加 50kg
TD.97184 version of AIN-93G suitable for irradiation (vitamin levels are increased) 适合辐照的AIN-93G 饲料 维生素含量增加 50kg
TD.00102 version of AIN-93M suitable for irradiation (vitamin levels are increased) 适合辐照的AIN-93M 饲料 维生素含量增加 50kg
TD.95092 modification of AIN-93G where soybean oil is replaced with corn oil. AIN-93G饲料 豆油改为玉米油 50kg
TD.06414 Adjusted Calories Diet (60/Fat) 卡路里调控饲料 60%脂肪 50kg
TD.06415 Adjusted Calories Diet (45/Fat) 卡路里调控饲料 45%脂肪 50kg
TD.03584 35% Lard Diet (Adj., No C) 35%猪油饲料 50kg
TD.93075 Adjusted Calories Diet (55/fat) 卡路里调控饲料 55%脂肪 50kg
TD.95217 Adjusted Fat Diet 脂肪控饲料 50kg
TD.96132 Adjusted Fat Diet 脂肪控饲料 50kg
TD.88137 Adjusted Kcal Diet (42% from fat 大卡调控饲料 42%脂肪 50kg
TD.08811 45% Kcal Fat Diet (21% MF, 2% SBO) 45%大卡脂肪饲料 42%脂肪 50kg
TD.06416 Adjusted Calories Diet (10/Fat) (a possible control for TD.06415 &
TD.06414 listed above) 卡路里调控饲料 10%脂肪 50kg
TD.08810 Low Glycemic Control Diet 低血糖饲料 50kg
TD.96355 Ketogenic Diet 生酮饲料 50kg
TD.84224 Essential Fatty Acid Deficient Diet 必须氨基酸缺损饲料 50kg
TD.88137 Adjusted Calories Diet (42% from fat) 卡路里调控饲料 42%脂肪 50kg
TD.88051 Cocoa Butter and Purina Chow Diet 椰子油和Purina Chow饲料 50kg
TD.90221 Cocoa Butter Diet with 75% Purina Mouse (5015)   50kg
TD.94059 5015, Cocoa Butter, Chol., etc. (excludes cholate)   50kg
TD.02028 Atherogenic Rodent Diet (1.25% Chol. & 0.5% Cholic Acid) 50kg
TD.01383 2018 + 2% Cholesterol   50kg
TD.86143 Vitamin A Deficient Diet 50kg
TD.89123 Vitamin D Deficient Diet 50kg
TD.88163 Vitamin E Deficient Diet 50kg
TD.95247 Folic Acid Deficient Diet 50kg
TD.80396 Iron Deficient Diet   50kg
TD.85419 Zinc Deficient Diet   50kg
TD.88239 Potassium Deficient Diet 50kg
TD.95027 Low Calcium Diet (0.4% P) 50kg
TD.96348 Diet (20% Lactose, 2% Ca, 1.25% P) 50kg
TD.92163 Selenium Deficient Diet   50kg
TD.95125 Iodine Deficient (0.15% PTU) 50kg
TD.93328 Protein Free Diet   50kg
TD.90016 6% Protein Diet   50kg
TD.91352 20% Protein Diet   50kg
TD.90018 40% Protein Diet   50kg
TD.89247 60% Fructose Diet   50kg
TD.86489 Diet with Adjusted Sucrose/Cornstarch   50kg
TD.96348 Diet (20% Lactose, 2% Ca, 1.25% P)   50kg
TD.98090 70% Carbohydrate Diet   50kg
TD.96355 Ketogenic Diet (almost no carbohydrate)50kg
TD.99366 Amino Acid Diet   50kg
TD.90262 Methionine & Choline Deficient Diet 50kg
TD.00434 Folic Acid Deficient Diet   50kg
TD.99386 No Lysine AA Diet   50kg
TD.90228 Sodium Deficient Diet   50kg
TD.96208 0.49% NaCl Diet   50kg
TD.90229 1% NaCl Diet   50kg
TD.92034 4% NaCl Diet   50kg
TD.92012 8% NaCl Diet   50kg
TD.01306 Rodent Diet (2018 + 625 doxycycline)   50kg
TD.98186 Rodent Diet (7012 + 200 doxycycline)   50kg
TD.92033 Swine Diet (15% Lard, 1.2% Cholesterol) 50kg
TD.92052 Swine Diet (15% Lard, 1.5% Cholesterol) 50kg
TD.93296 Swine Diet (15% Lard, 2% Cholesterol)   50kg
CA.40060 Teklad Vitamin Mix   50kg
CA.40077 AIN-76A Vitamin Mix   50kg
TD.94047 AIN-93 Vitamin Mix   50kg
CA.170915 AIN-76 Mineral Mix   50kg
TD.94046 AIN-93G Mineral Mix   50kg
TD.94049 AIN-93M Mineral Mix   50kg