Hampton蛋白悬滴结晶板 HDP Hanging Drop Crystallization Plate
美国Hampton Research公司位于加利福尼亚州，是一家专门从事蛋白质晶体研究的生产商。该公司向全球科研人员提供全面的晶体研究试剂和相关实验耗材，同时提供晶体设计和合成方面的定制服务。Hampton Research公司以其先进的生物大分子结晶技术和广泛实用的产品线，不仅为全世界晶体研究人员的工作带来了便捷，而且也受益于科研人员的回馈不断发展自己，目前已成为晶体研究领域最受信赖的品牌之一。
Hampton research主要产品：
Crystallization Screens 用于筛选和优化蛋白质/多肽/核酸结晶的一系列经验证的高精配方型溶液
Optimize Reagents 结晶级别盐类，聚合物，有机溶液或缓冲液
Crystallization Plates, Hardware & Accessories 结晶板（悬滴法和坐滴法，微量透析，微配液，自由界面扩散，凝胶以及无容器悬浮法）及其他配件
Cryocrystallography 低温晶体学耗材如 Crystalcap system,cryoloops
Goniometer Heads&Supplies 测角器头和配件
Protein Crystallization Standards 结晶级别标准蛋白
Custom Shop Crystallization Reagents 定制试剂盒和结晶溶液内的单一组分
StockOptions Kits 内含盐类，缓冲液和冷冻液的简便型试剂盒
Tools，Seeding&Resin 结晶用探针，结晶笔，seeding法结晶工具
Capillary Mounts & Supplies 毛细管,玻璃纤维, 蜡,黏合剂和密封剂
Hampton蛋白悬滴结晶板 HDP Hanging Drop Crystallization Plate

HDP Hanging Drop Plate

Single Well with Tool

Hanging Drop Wells
Applications—Hanging drop crystallization
Features
  Made from optically superior polymer (UVP)
  Allen key novel crystal plug closure system
  Wells are micro-numbered
Description  描述：
The Swissci Hanging Drop Crystallization Plate is a breakthrough for protein crystallization in a 96-well format. For the first time individual wells can be identified and removed without any disturbance to the growing crystals inside the plate.Description
The plate has been developed by Swissci AG together with leading Crystallographers. It is the result of many years of experience in successful robotic high-throughput crystallization.
The Hanging Drop Crystallization Plate offers unique properties that make it ideal for both nanoliter crystallization screening and microliter optimization alike. Made from optically superior polymer (UVP) and with a new design of the wells, the plate allows easy crystal viewing and retrieval. The system is fully covered by design and patent protection.
The Advantages of the Hanging Drop Crystallization Plate
Easy Crystal Retrieval
Raised wide wells make the crystal mounting especially easy. Allen key system allows for smooth removal and subsequent microscopic investigation / X-ray with the novel crystal plug closure all included in the system.
Easy Viewing
The wells are wide conical and have a lens effect for perfect illumination. The micro-numbering ensures you will never loose the location under the microscope.
The optically superior polymer is UV transmissible and can be used to differentiate between salt and protein crystals.
Integral Sealing
Wide partition walls between each well provides a high surface area for very good sealing with the advanced quality sealing tape. The sealing tape is integrated into the kit so there is no need to purchase additional parts prior to starting a procedure.
Wide Range of Volumes
Typical volumes are 50 – 200 µl of reservoir and 10 nanoliter – 5 microliter drop size.
SBS Standard
The complete plate is designed to the 96-well SBS standard for all common holders.

Hampton蛋白悬滴结晶板 HDP Hanging Drop Crystallization Plate 相关产品：

Wizard Tube 
The Wizard™ Classic line of random sparse matrix screens is designed to increase your probability of producing crystals during the coarse screening phase when crystallizing biological macromolecules (proteins, nucleic acids, peptides, and combinations thereof).
The Wizard Classic reagents are proven to be a highly effective starting point in the screening of biological macromolecules. The Wizard Classic formulations include a large range of crystallants, buffers, and salts covering a broad range of crystallization space at pH levels from pH 4.5 to pH 10.5.Choose from Wizard Classic 1, 2, 3, or 4 non-overlapping formulations in matrix blocks or tubes.

Wizard Cubic LCP
The tools in the Wizard Cubic LCP (lipidic cubic phase) Kit enable researchers to prepare LCP-type crystallizations by hand. Ideal for low-protein experiments: effective protein volume for a single crystallization experiment is about 80 nanoliters. Wizard Cubic LCP Kit tools work especially well when traditional methods have failed to yield crystals. Lipidic cubic phase has worked well for the crystallization of 7TM membrane proteins (proteins with seven transmembrane helices). Four out of six GPCRs (G-protein coupled receptors), an important membrane protein class, and several microbial 7TM proteins have been crystallized using the LCP approach.

CRYO (I、II)
The Wizard Cryo™ line of random sparse matrix screens is designed for scientists who want to avoid the additional step of optimizing a cryoprotectant condition. Every Wizard Cryo formulation flash-freezes to a clear, amorphous glass in liquid nitrogen or in a cryo-stream at 100K. Crystals can be frozen directly from their growth drops, avoiding the additional step of pre-equilibration with an artificial cryo-condition that can damage the crystal. Eleven different cryocrystallants and sparing use of glycerol ensures a broad sampling of possible cryo conditions. Choose from Wizard Cryo 1 or 2 formulations in tubes or Wizard Cryo 1 and 2 together in a 96-well matrix block.

Hampton蛋白质结晶捞针（结晶环）18 mm Mounted CryoLoop™

Applications

Cryocrystallography

Features

		Adjustable loop orientation
		Synthetic CryoLoop on adjustable stainless steel MicroTube
		MicroTube specially engineered with EasySnap notches
		20 micron diameter nylon CryoLoop

Description
Similar to the Mounted CryoLoop™ in design and function, the Adjustable Mounted CryoLoop allows one to manipulate and orient the CryoLoop to multiple, unique positions previously unattainable with typical cryo setups. The Adjustable Mounted CryoLoop is a 20 micron diameter synthetic loop mounted inside a malleable stainless steel sleeve, which in turn, is mounted inside the EasySnap MicroTube™.
Using a specially designed L-shaped tool (HR5-902) with a positioning notch, one can manipulate the angle and orientation of the CryoLoop by bending and adjusting the angle of the malleable stainless steel insert which holds the CryoLoop. The Adjustable Mounted CryoLoop may be positioned several times. Note: Repeated manipulation will fatigue the sleeve which can lead to failure of the sleeve. The Adjustable Mounted CryoLoop is designed to work with the CrystalCap System components.
The MicroTube is 24 mm in length and is specially engineered with EasySnap™ notches at the 10, 12, 14, 18, and 21 mm measures. To obtain the desired length of MicroTube, simply snap the MicroTube at the desired length and stake it to the CrystalCap™ Magnetic or CrystalCap™ Copper Magnetic. These nylon loops show minimal diffraction, are thin for fast freezing, strong, and aerodynamic.
Most data collection geometries prefer or require a 22 mm length between the base of the cap and the beam. For a 22 mm overall length using the CrystalCap, CrystalCap ALS, CrystalCap ALS HT and CrystalCap SPINE HT, snap the MicroTube at the second notch from the bottom, creating an 18 mm MicrozTube lenghth and secure to the CrystalCap using epoxy or similar adhesive. For a 22 mm over length using the CrystalCap Copper, CrystalCap Copper HT, CrystalCap ALS Copper HT snap the MicroTube at the fifth notch from the bottom (notch closest to the CryoLoop) and secure to the CrystalCap using epoxy or similar adhesive.
The HR5-902 Tool for Adjustable Mounted CryoLoop is not included with the Adjustable Mounted CryoLoop and must be purchased as a separated item.

18 mm Mounted CryoLoop

18 mm Mounted CryoLoop properly installed in a CrystalCap Magnetic

Crystal in CryoLoop

Hampton 0.1毫米50号玻璃毛细管

货号：HR6-104
包装：25 pack

• 英文名：0.1 mm Glass Number 50 Capillary
• 品牌：Hampton

Hampton代理–金畔生物

硼硅玻璃50号毛细管壁厚0.01毫米，全长80毫米+ / – 5毫米。提供外径从0.1毫米到2毫米的毛细管，用于X射线数据收集，晶体密度测量和晶体生长实验。毛细管可以用蜡，环氧树脂等密封材料封闭，防止水分和气体。

应用
X射线数据采集
液-液扩散结晶
凝胶针状结晶
特征
50号硼硅玻璃
壁厚 10微米
描述
硼硅玻璃50号毛细管一端呈漏斗形，另一端封闭，壁厚0.01毫米，全长80毫米+/-5毫米，外径从0.1毫米到2毫米。可嵌入，盛放，储存小分子和生物大分子晶体用于X射线数据收集，晶体密度测量和晶体生长实验。毛细管可以用蜡，环氧树脂和其它密封材料密封，防止水分和气体。
请参照“线性吸收系数µcm-1表“，以决定适合的玻璃/石英玻璃毛细管。本表展示的是X射线数据收集时的辐射吸收量。
0.1mm至2.0mm毛细管开口端的基础尺寸为：3.0+/-0.15mm外径 x 0.13+/-0.10 mm壁厚，直径为在毛细管封闭端40毫米处的测量值。
 

货号	产品说明	公差
HR6-104	Size: 0.1 mm – 25 pack	0.1 mm -0.075 / +0.075 mm
HR6-106	Size: 0.2 mm – 25 pack	0.2 mm -0.050 / +0.050 mm
HR6-108	Size: 0.3 mm – 25 pack	0.3 mm -0.050 / +0.100 mm
HR6-110	Size: 0.4 mm – 25 pack	0.4 mm -0.100 / +0.100 mm
HR6-112	Size: 0.5 mm – 25 pack	0.5 mm -0.100 / +0.100 mm
HR6-114	Size: 0.6 mm – 25 pack	0.6 mm -0.100 / +0.100 mm
HR6-116	Size: 0.7 mm – 25 pack	0.7 mm -0.150 / +0.150 mm
HR6-118	Size: 0.8 mm – 25 pack	0.8 mm -0.150 / +0.150 mm
HR6-120	Size: 0.9 mm – 25 pack	0.9 mm -0.150 / +0.150 mm
HR6-122	Size: 1.0 mm – 25 pack	1.0 mm -0.150 / +0.250 mm
HR6-124	Size: 1.5 mm – 25 pack	1.5 mm -0.250 / +0.250 mm
HR6-126	Size: 2.0 mm – 25 pack	2.0 mm -0.250 / +0.250 mm

Hampton 水晶透明密封带Crystal Clear Sealing Tape

3 inch, 1.88 inch, 1.88 inch with dispenser, 0.75 inch with dispenser (left to right)

0.75 inch Crystal Clear Sealing Tape
Applications  应用
Sealing tape used to seal sitting drop crystallization experiments
Description
These optically clear tapes are compatible with protein crystallization reagents. The polypropylene Crystal Clear Sealing Tapes use acrylic solvent based adhesives which are compatible with aqueous crystallization reagents.
Catalog number HR3-511 is a 1.88 inch (48 mm) wide, 3 mil tape on a 43.7 yard (40 M) roll with a 1.5 inch core and is supplied with a green dispenser / cutter.Catalog number HR4-511 is a 1.88 inch wide, 3 mil tape on a 60 yard roll with a 3 inch core and no dispenser / cutter.Two strips of the HR3-511 or HR4-511 will seal a Corning, Cryschem, CrystalClear Strip, Greiner, Intelliplate, Linbro, Swissci (MRC), VDX and VDXm plate.Catalog number HR4-506 is a 3 inch wide, 3 mil tape on a 54.86 yard roll with a 3 inch core and no dispenser / cutter.One strip of the HR4-506 will seal a Corning, Cryschem M, CrystalClear Strip, Greiner, Intelliplate, Swissci (MRC) and VDXm plate.Crystal Clear Mini Sealing Tape HR4-508 is a 0.75 inch (19 mm) wide, 3 mil tape on a 650 inch (16.5 M) roll and is supplied with a clear dispenser / cutter. The tape is useful for resealing or patching wells after mounting crystals. The tape is also wide enough to seal a single row of a Cryschem S or Cryschem M plate.See chart for tape and plate compatibility.

Hampton结晶用缓冲盐试剂盒– SaltRx
SaltRx 1 • SaltRx 2 • SaltRx HT

Hampton蛋白结晶工具及仪器
CryoTong™ – Long
ApplicationsCrystal transfer under cryo temperature
FeaturesArtery clamp style closure30 seconds of cryo temperature180 mm length
Description
The CryoTong is a tool used to manually transfer a crystal mounted on a CrystalCap™ from liquid nitrogen to a magnetic base in a goniometer head positioned in a cryogenic stream, and then back to liquid nitrogen. The one-piece, compact CryoTong is available in two lengths. The long CryoTong is approximately 180 mm in overall length. The artery clamp style maintains the CryoTong in the closed position until the clamp is squeezed, which opens the opposing heads. The heads are non-magnetic stainless steel. The handle is magnetic stainless steel. The inside of the head is machined to closely surround the CrystalCap with loop and crystal in place. A small retaining lip is machined into the lower portion of the head to prevent the CrystalCap from slipping out of the CryoTong when the tool is in the closed position. The CryoTong can maintain the temperature of the crystal at -160°C for up to 30 seconds during room temperature crystal transfers. Choose the proper CryoTong size based upon the pin length required by the configuration of the x-ray data collection hardware used. The 18 mm CryoTong (HR5-112) is to be used with the CrystalCap HT and any other CrystalCap configured for 18 mm.HR5-114 Long CryoTong 18 mm, 180° features the head in alignment with the handle of the CryoTong.

Vial Clamp™ – Straight
ApplicationsVial support and manipulation
FeaturesStraight end tipHemostat style closureDescription
The Vial Clamp™ – Straight is a chrome plated, hemostat style tool. It has a tip shaped to hold the storage vial of all the CrystalCap Systems™ straight when the clamp is closed. The clamp can be locked using the hemostat style closure. This clamp makes it easy to dip the storage vial into liquid nitrogen for crystal storage. The complete length of the clamp is straight, with an overall length of 195 mm. When the vial is placed in the clamp, the length of it is positioned perpendicular, 90° to the length of the clamp.

CrystalWand™ Magnetic
ApplicationsCrystalCap Magnetic & CrystalCap Copper Magnetic handling toolDescription
The CrystalWand Magnetic is designed to be used exclusively with the CrystalCap Magnetic, CrystalCap Copper Magnetic, and CrystalCap HT systems during transfer of the caps from the vial to the goniometer head and from the goniometer to the vial. The 6 1/2” (165 mm) long chrome plated steel wand features a plastic housing enclosing a spring tensioned plunger that when depressed, moves a non-magnetic steel platform away from the magnet housed in the end of the wand. This causes the steel CrystalCap to detach from the wand and be placed readily into the vial or the CryoTong™. When the platform is retracted, the wand securely holds the steel CrystalCap Magnetic. The CrystalWand Magnetic 45° (McMiken Tool) offers the same functionality but is bent at a 45° angle at approximately 2.5 cm from the magnet end.HR4-729 CrystalWand Magnetic, StraightHR4-315 CrystalWand Magnetic, 45° (McMiken Tool)

Vial Clamp™ – Curved
ApplicationsVial support & manipulation
FeaturesCurved end tipHemostat style closureDescription
The Vial Clamp – Curved is a chrome plated, hemostat style tool. It has a tip shaped to hold the storage vial of all the CrystalCap Systems at an angle when the clamp is closed. The clamp can be locked using the hemostat style closure. The end of the clamp, where the vial is held, is curved at either a 45°/135° or 110°/ 70° angle. When the vial is placed in the clamp, the length of it is positioned to the clamp at either of those same angles. The overall length of each clamp is the same, 195 mm.HR4-671 Vial Clamp – Curved 45°/135°HR4-672 Vial Clamp – Curved 110°/70°

CrystalCap™ Holder
pplicationsCrystalCap support inside stainless steel dewars
FeaturesAdjustable heightSupports up to 8 CrystalCaps15 ml vial position for liquid propane500 and 1,000 ml versionsDescription
CrystalCap Holders are convenient stands for holding all CrystalCap™ systems in liquid nitrogen dewars during crystal cryogenic procedures. Available in two sizes. Both holders feature spring-clips to secure the CrystalCap Vials in the holder. Both stands have 3 inches of adjustable Z (height) which allows one to raise or lower the CrystalCaps to the appropriate height, depending upon the liquid nitrogen level in the dewar. Each holder is supplied with a socket driver for height adjustment.500 ml version holds five CrystalCaps, two 15 ml vials (for liquid propane procedures) and fits into the 500 ml dewar. 1,000 ml version holds eight CrystalCaps, two 15 ml vials (for liquid propane procedures) and fits into the 1,000 ml dewar.HR4-707 CrystalCap Holder – 500 ml
HR4-706  Replacement Height Adjustment Tool

Hampton Natrix • Natrix 2 • Natrix HT

Applications
  Primary biased sparse matrix crystallization screen for nucleic acids & protein/nucleic acid complexes  主要用于核酸和蛋白质/核酸复合物的删选

Crystals of a frameshift promoting RNA pseudoknot from the coronavirus IBV, grown using the Hampton Research Natrix screen. Simon Pennell, MRC National Institute for Medical Research, United Kingdom.

View Full Size

Crystals of Ec Rnk, a new RNA polymerase interacting protein obtained in Hampton Research Natrix Screen. Valerie Lamour, IGBMC, Illkirch, France.

 

CAT NO	NAME	DESCRIPTION
HR2-116	Natrix	10 ml, tube format
HR2-117	Natrix 2	10 ml, tube format
HR2-131	Natrix HT	1 ml, Deep Well block format