HMGBIOTECH 高迁移率蛋白、质粒、抗体
hmgbiotech HM-120
HMGB 1是细胞核的一个组成部分，在基因组的组织和表达中具有多种功能。HMG生物技术SRL为活跃在这一领域的其他研究人员和公司提供试剂、服务和想法。它还有助于实验室开发分析和试剂。
hmgbiotech DISULFIDE HMGB1说明书
hmgbiotech HM-120
HMGB1是一种核蛋白，其由坏死细胞被动释放，由凋亡细胞保留，并由炎症细胞主动分泌（Dumitriu等人，HMGB1:从内部引导免疫。Trends Immunol 2005，26:381-7）。HMGB1对生命至关重要：HMGB1基因敲除小鼠出生后不久死亡。
HMGB1作为运动细胞的化学引诱剂和细胞因子的诱导剂的两种不同活性被归因于不同的生物化学形式。还原的HMGB1（具有化学引诱活性的形式）被还原；二硫化物HMGB1包含C23和C45之间的二硫键（完整注释：HMGB1C23-C45C106h–Antoine J.等人（2014）。Mol-Med）。
二硫化物HMGB1可诱导单核细胞和其他炎症细胞产生细胞因子和趋化因子（Venereau等人，2012）。
在结构上，二硫化物HMGB1在半胱氨酸残基23和45与还原的半胱氨酸残基106之间具有二硫键。测试二硫化物HMGB1刺激细胞因子的能力
HMGBiotech公司热销产品
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产品名称 |
货号 |
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100 ug Fully reduced HMGB1, LPS free |
HM-115 |
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50 ug Fully reduced HMGB1, LPS free |
HM-116 |
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100 ug Disulfide HMGB1, LPS free |
HM-121 |
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100 ug BoxA from HMGB1, LPS-free and tested in migration assay |
HM-012 |
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50 ug Disulfide HMGB1, LPS free |
HM-122 |
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500 ug BoxA from HMGB1, LPS-free and tested in migration assay |
HM-013 |
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1 mg HMGB1 for biochemistry |
HM-100 |
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2.5 mg BoxA from HMGB1, LPS-free and tested in migration assay |
HM-014 |
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250 ug HMGB1 biochemistry |
HM-101 |
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25 ug BoxA from HMGB1, LPS-free and tested in migration assay |
HM-011 |
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15 ug BoxB from HMGB1, LPS-free and tested in migration assay |
HM-053 |
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15 ug Fully reduced HMGB1, LPS free |
HM-117 |
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10 ug Disulfide HMGB1, LPS free |
HM-123 |
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15 ug Non-oxidizable HMGB1, LPS free |
HM-133 |
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250 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration |
HM-170 |
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100 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration |
HM-171 |
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50 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration |
HM-172 |
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15 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration |
HM-173 |
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50 ug HMGB1 15N labelled for Mass Spectrometry |
HM-180 |
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5 ug HMGB1 15N labelled for Mass Spectrometry |
HM-181 |
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2.5 mg BoxA 2D from HMGB1, LPS-free and tested in migration assay |
HM-190 |
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500 ug BoxA 2D from HMGB1, LPS-free and tested in migration assay |
HM-191 |
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100 ug BoxA 2D from HMGB1, LPS-free and tested in migration assay |
HM-192 |
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25 ug BoxA 2D from HMGB1, LPS-free and tested in migration assay |
HM-193 |
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Control cell lysates from Hmgb1 +/+ |
HM-001 |
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Control cell lysates from Hmgb1 -/- |
HM-002 |
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1 mg BoxB from HMGB1, LPS-free and tested in migration assay |
HM-050 |
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250 ug BoxB from HMGB1, LPS-free and tested in migration assay |
HM-051 |
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100 ug BoxB from HMGB1, LPS-free and tested in migration assay |
HM-052 |
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500 ug Fully reduced HMGB1, LPS free |
HM-114 |
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250 ug Disulfide HMGB1, LPS free |
HM-120 |
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500 ug Non-oxidizable HMGB1, LPS free |
HM-130 |
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100 ug Non-oxidizable HMGB1, LPS free |
HM-131 |
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50 ug Non-oxidizable HMGB1, LPS free |
HM-132 |
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500 ug HMGB2, LPS-free and tested in migration assay |
HM-151 |
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100 ug HMGB2, LPS-free and tested in migration assay |
HM-152 |
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50 ug HMGB2, LPS-free and tested in migration assay |
HM-153 |
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Embryonic fibroblasts immortalized with large T antigen. One vial of -/- cells and one vial of +/+ cells |
HM-201 |
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Embryonic fibroblasts immortalized with the 3T3 method. One vial of -/- cells and one vial of +/+ cells |
HM-221 |
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Embryonic fibroblasts, Hmgb1-/- and HMGB2-low, immortalized with the 3T3 method. One vial of cells, and |
HM-223 |
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HMGB1 Isoforms Kit – Test size |
HM-030 |
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Embryonic fibroblasts immortalized with the 3T3 method. One vial of Hmgb2-/- cells and one vial of +/+ cells |
HM-251 |
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HMGB1 Isoforms Kit – Regular size |
HM-031 |
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20 ug p-mHMG1 |
HM-300 |
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50 ug Terminally oxidized HMGB1, LPS free |
HM-062 |
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20 ug p-mHMG1tag |
HM-301 |
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100 ug Terminally oxidized HMGB1, LPS free |
HM-061 |
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20 ug pEGFP-HMGB1 |
HM-302 |
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250 ug Terminally oxidized HMGB1, LPS free |
HM-060 |
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20 ug pcDNA/FL-RAGE plasmid |
HM-310 |