PhoenixSongs PSB神经模型

 

 

PhoenixSongs是一家性的生命科学公司,致力于开发和提供用于研究和药物发现的新型干细胞衍生模型系统。

我们的干细胞来源包括从人体组织中分离的iPS细胞和干细胞,如肝脏,脑,胆管树和脐带。我们拥有强大的知识产权组合以及*的学术专业知识和药物发现工具产品开发的悠久历史。

Human / Human™模型代表了一个*由人类衍生的系统,该系统具有良好的特征,适合长期培养(> 30天),同时在30多个过程中保持细胞色素P450,II期和药物转运基因的表达。

PSB神经模型

 

 

从人脑组织中分离出人HIP-009神经干细胞

 

分化为多种神经亚型星形胶质细胞和少突胶质细胞。

 

VGAT/VGlut

 

TUJ-1/突触素

 

标度>109细胞,结果一致

 

专为生长、过渡和定向分化而设计的培养基,以丰富特定的神经亚型。

 

电生理学膜片钳和多电极阵列(MEAS)测量功能的人神经元

 

兼容高通量筛选(HTS)平台

 

 

泛神经模型

 

自发动作电位

 

具有谷氨酸能和GABA能特征的自发网络活动。

 

与高含量端点相关良好

 

HIP-009神经干细胞分化为成熟的功能泛神经元。

 

28天后,用10mmA-Beta(Ab)寡聚体1-42作用24小时后,对Tuj 1、GFAP和突触素进行固定和免疫染色。

 

图像分析是在细胞组学VTI上进行的。

 

高含量分析表明,Ab42个寡聚体引起的突触缺陷明显。

 

这种模型正被用于筛选预防/治疗阿尔茨海默氏病的药物。

 

HIP-009神经干细胞在MEA上分化为PAN神经元,并在70天以上的培养中维持。

 

HIP-009人神经元对苦毒素(10 M)的典型反应与大鼠原代神经元相当。

 

车辆控制(DMSO 0.2%)-数据未显示

 

对于栅格图像,选择了具有代表性的电极。

 

光栅情节显示

 

燃烧速度,加热速度

 

成组传送速率

 

脉冲时间

 

同步(性)

 

活性电极数

 

DA-H9神经干细胞在MEA上分化为多巴胺能神经元

 

70%的神经元为TH。

 

发展的具有尖峰和爆发的神经网络

 

剂量响应曲线对MPP的响应

 

该模型用于筛选治疗/预防帕金森病的药物。

 Phoenixsongsbio 部分产品如下:

货号

品名

规格

品牌

11005-050

StemCell Freezing Media

50ml

phoenixsongsbio

12001-024

Biomatrix Coated 24-well Plates (5 plates/box)

5

phoenixsongsbio

12001-096

Biomatrix Coated 96-well Plates clear (5 plates/box)

5

phoenixsongsbio

12003-096

Biomatrix Coated 96-well Plates white/clear (5 plates/box)

5

phoenixsongsbio

12004-060

Biomatrix Coated 60mm Dishes (10 dishes/sleeve

10

phoenixsongsbio

13002-010

Donor Lot FL-1010

4M cells

phoenixsongsbio

13002-014

Donor Lot FL-1014

4M cells

phoenixsongsbio

15001-010

Donor Lot FBT-1010

2M cells

phoenixsongsbio

15001-055

Donor Lot FBT-1055

2M cells

phoenixsongsbio

CRM050

Cryopreserved Hepatocyte Recovery Media

50ml

phoenixsongsbio

HCM500

Hepatocyte Culture Media

500ml

phoenixsongsbio

PHHCCP

Primary Human Hepatic Co-Culture Plates

Ea.

phoenixsongsbio

33002-018GA

Donor Lot LMSC-18

5M Cells

phoenixsongsbio

33002-1007GA

Donor Lot LMSC-1007

5M Cells

phoenixsongsbio

33002-1012GA

Donor Lot LMSC-1012

5M Cells

phoenixsongsbio

PHHCCK

Human / Human Hepatic Model Kit

Ea.

phoenixsongsbio

35002-010

Frozen FL-HCC Spheroids – Donor Lot Tu-2010

0.5-1M Cells

phoenixsongsbio

35301-030

FL-HCC Spheroid Dissociation Media

30ml

phoenixsongsbio

35201-050

FL-HCC Spheroid Freezing Media

50ml

phoenixsongsbio

11001-250

Kubota's StemCell Growth Media

250ml

phoenixsongsbio

11003-250

Hepatic Differentiation Media

250ml

phoenixsongsbio

11006-500

Wash Buffer

500ml

phoenixsongsbio

12001-006

Biomatrix Coated 6-well Plates (5 plates/box)

5

phoenixsongsbio

12001-048

Biomatrix Coated 48-well Plates (5 plates/box)

5

phoenixsongsbio

12002-096

Biomatrix Coated 96-well Plates black/clear (5 plates/box)

5

phoenixsongsbio

12004-100

Biomatrix Coated 100mm Dishes (10 dishes/sleeve)

10

phoenixsongsbio

12005-012

Biomatrix Suspension

1

phoenixsongsbio

13002-013

Donor Lot FL-1013

4M cells

phoenixsongsbio

13002-015

Donor Lot FL-1015

4M cells

phoenixsongsbio

15001-020

Donor Lot FBT-1020

2M cells

phoenixsongsbio

HPM250

Hepatocyte Plating Media

250ml

phoenixsongsbio

33002-1006GA

Donor Lot LMSC-1006

5M Cells

phoenixsongsbio

33002-1009GA

Donor Lot LMSC-1009

5M Cells

phoenixsongsbio

35101-250

Kubota’s FL-HCC Spheroid Growth Media

250ml

phoenixsongsbio

35302-500

Spheroid Wash Buffer

500ml

phoenixsongsbio

11002-250

Kubota's Hepatoblast Growth Media

250ml

phoenixsongsbio

13001-001

Donor Lot NL-1001

4M cells

phoenixsongsbio

21001-250

Neural StemCell Growth Media (Human and Rat )

250 ml

phoenixsongsbio

21002-250

Dopaminergic Differentiation Media

250 ml

phoenixsongsbio

21003-250

Neural Transition Media

250 ml

phoenixsongsbio

21004-250

Neural Differentiation Media

250 ml

phoenixsongsbio

21005-050

Neural Freezing Media

50 ml

phoenixsongsbio

21006-050

Neuron Freezing Media

50 ml

phoenixsongsbio

23001-001

Donor Lot CxB-1

1.5M cells

phoenixsongsbio

23001-002

Donor Lot CxB-2

1.5M cells

phoenixsongsbio

23001-003

Donor Lot CxB-3

1.5M cells

phoenixsongsbio

23001-004

Donor Lot CxB-4

1.5M cells

phoenixsongsbio

23001-009

Donor Lot CxB-009

1.5M cells

phoenixsongsbio

23002-003

Donor Lot HIP-3

1.5M cells

phoenixsongsbio

23002-005

Donor Lot HIP-005

1.5M cells

phoenixsongsbio

23002-009

Donor Lot HIP-009

1.5M cells

phoenixsongsbio

23003-003

Donor Lot MHB-3

1.5M cells

phoenixsongsbio

23003-004

Donor Lot MHB-4

1.5M cells

phoenixsongsbio

23005-001

Donor Lot RCxB-1

1.5M cells

phoenixsongsbio

23005-002

Donor Lot RCxB-2

1.5M cells

phoenixsongsbio

23006-001

Donor Lot RHIP-1

1.5M cells

phoenixsongsbio

23006-002

Donor Lot RHIP-2

1.5M cells

phoenixsongsbio

23007-001

Donor Lot RMHB-1

1.5M cells

phoenixsongsbio

23007-002

Donor Lot RMHB-2

1.5M cells

phoenixsongsbio

24001-002

Donor Lot CxB-2

Kit

phoenixsongsbio

24001-003

Donor Lot CxB-3

Kit

phoenixsongsbio

24001-004

Donor Lot CxB-4

Kit

phoenixsongsbio

24001-009

Donor Lot CxB-009

Kit

phoenixsongsbio

24002-003

Donor Lot HIP-3

Kit

phoenixsongsbio

24002-005

Donor Lot HIP-005

Kit

phoenixsongsbio

24002-009

Donor Lot HIP-009

Kit

phoenixsongsbio

24003-003

Donor Lot MHB-3

Kit

phoenixsongsbio

24003-004

Donor Lot MHB-4

Kit

phoenixsongsbio

24005-001

Donor Lot RCxB-1

Kit

phoenixsongsbio

24005-002

Donor Lot RCxB-2

Kit

phoenixsongsbio

24006-001

Donor Lot RHIP-1

Kit

phoenixsongsbio

24006-002

Donor Lot RHIP-2

Kit

phoenixsongsbio

24007-001

Donor Lot RMHB-1

Kit

phoenixsongsbio

24007-002

Donor Lot RMHB-2

Kit

phoenixsongsbio

25001-001

Donor Lot CxB-1

4-5M cells

phoenixsongsbio

25001-002

Donor Lot CxB-2

4-5M cells

phoenixsongsbio

25001-003

Donor Lot CxB-3

4-5M cells

phoenixsongsbio

25001-004

Donor Lot CxB-4

4-5M cells

phoenixsongsbio

25001-009

Donor Lot CxB-009

4-5M cells

phoenixsongsbio

25002-003

Donor Lot HIP-3

4-5M cells

phoenixsongsbio

25002-005

Donor Lot HIP-005

4-5M cells

phoenixsongsbio

25002-009

Donor Lot HIP-009

4-5M cells

phoenixsongsbio

25003-003

Donor Lot MHB-3

4-5M cells

phoenixsongsbio

25003-004

Donor Lot MHB-4

4-5M cells

phoenixsongsbio

25004-009

Donor Lot DA-H9

4-5M cells

phoenixsongsbio

25005-001

Donor Lot RCxB-1

1.5M cells

phoenixsongsbio

25005-002

Donor Lot RCxB-2

1.5M cells

phoenixsongsbio

25006-001

Donor Lot RHIP-1

1.5M cells

phoenixsongsbio

25006-002

Donor Lot RHIP-2

1.5M cells

phoenixsongsbio

25007-001

Donor Lot RMHB-1

1.5M cells

phoenixsongsbio

25007-002

Donor Lot RMHB-2

1.5M cells

phoenixsongsbio

27001-009

HIP-9 Transitioned Neural Stem Cells

1.5M cells

phoenixsongsbio

27002-009

DA-H9 Dopaminergic Neural Stem Cells

1.5M cells

phoenixsongsbio

41001-500

D-PBS w/ Ca++, Mg++

500 ml

phoenixsongsbio

41002-500

D-PBS w/o Ca++, Mg++

500 ml

phoenixsongsbio

41004-100

Trypsin, Hank’s based 0.05% Trypsin, 0.5 mM EDTA

100 ml

phoenixsongsbio

41005-100

Soybean Trypsin Inhibitor 0.025% in PBS

100 ml

phoenixsongsbio

 

 

 

上海金畔生物科技有限公司是实验试剂一站式采购服务商

1:强大的进口辐射能力,血清、抗体、耗材、大部分限制进口品等。

2:产品种类齐全,经营超过700多个品牌,基本涵盖所有生物实验试剂耗材。

3:提供加急服务,货品一般1-2周到货。

4:富有竞争力的价格优势,绝大部分价格有优势。

5:多年积累良好的信誉,大部分客户提供货到付款服务。客户包括清华、北大、交大、复旦、中山等100多所高校,ROCHE,阿斯利康、国药、fisher等药企。

6:我们还是Santa,Advanced Biotechnologies Inc,Athens Research & Technology,bangs,BBInternational,crystalchem,dianova,FD Neurotechnologies,Inc. FormuMax Scientific,Inc, Genebridege, Glycotope Biotechnology GmbH; iduron,Innovative Research of America, Ludger, neuroprobe,omicronbio, Polysciences,prospecbi, QA-BIO,quickzyme,RESEARCH DIETS,INC,sterlitech;sysy,TriLink BioTechnologies,Inc;worthington-biochem,zyagen等几十家国外公司代理。

7:我们还是invitrogen,qiagen,MiraiBioam,sigma;neb,roche,merck, rnd,BD, GE,pierce,BioLegend等*批发,欢迎合作。