pentapharm公司产品

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pentapharm公司产品

简要描述：Pentapharm总部位于瑞士Kaiseraugst 的DSM营养品公司，靠近巴塞尔，拥有日本、巴西等
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蛋白酶抑制剂

合成，低分子量丝氨酸蛋白酶抑制剂。范围包括竞争力，以及不可逆抑制剂。应用：去除不需要的蛋白水解酶活性，增加色底物检测的特异性或保护特定的蛋白质水解降解。

 

099-11

 Pefabloc®FG H-Gly-Pro-Arg-Pro-OH×AcOH
099-01 Inhibits fibrin polymerisation 　
126-05 r-Hirudin C287H440N80O110S6
　 Inhibits thrombin 　
380-03 Pefabloc®PK C24H26N4O3S×HCl
　 For the determination of plasma kallikrein 　
381-01 Pefabloc® TH C27H31N5O4S×AcOH
　 For the determination of thrombin 　
381-02 Pefabloc®TH1158 C27H32N6O4S×HCl
　 For the determination of thrombin 　
382-03 Pefabloc®uPA C32H47N5O5S×HCl
　 For the determination of urokinase 　
383-03 Pefabloc®PL C31H33N5O4S2×HCl
　 For the determination of plasmin 　
384-01 Pefabloc®Try C14H12N2O2×HCl×H2O
　 For the determination of trypsin-like 　
384-04 Pefabloc®Try1405 C26H29N5O5S×HCl
　 For the determination of trypsin 　
385-02 H-Glu-Gly-Arg-CMK C14H25N6O5Cl×2TFA
　 For the determination of serine proteases 　
385-03 Pefabloc®Xa C20H24N4O5S×HCl
　 For the determination of Factor Xa 　
390-10 Pefabloc®Tryp C44H44N8O6S2×2HCl
　 For the determination of mast cell typtase 　
391-03 Pefabloc®tPA/Xa C23H24N4O×2HCl
　 For the determination of tPA/Xa 　
398-01 Pefabloc®SP C10H10N2O3×HCl
　 For the determination of trypsin-like serine proteases 　
399-01 Pefabloc®SC C8H10FNO2S×HCl
　 For the determination of serine proteases 　
800277 （1g） Aprotinin 　
800348 （100g） Inhibits serine proteases

 

 

 

 

 　

 

Chromogenic Substrates for Thrombin

 

081-01

 Pefachrome® TH 5244 Tos-Gly-Pro-Arg-pNA ·AcOH
081-03 Pefachrome® TH H-D-CHG-Ala-Arg-pNA · 2AcOH
081-05 Pefachrome® TH 5247 H-D-CHG-But-Arg-pNA · 2AcOH
081-08 Pefachrome® TH 5250 H-D-CHG-Pro-Arg-pNA · 2AcOH
081-09 Pefachrome® TH 5251 H-D-CHA-Ala-Arg-pNA · 2AcOH
081-10 Pefachrome® TH 5252 H-D-CHA-Gly-Arg-pNA · 2AcOH
081-11 Pefachrome® TH 5253 H-D-CHA-Gly-Arg-pNA · 2AcOH
081-15 Pefachrome® TH 5256 CH3OCO-Gly-Pro-Arg-pNA · AcOH
081-17 Pefachrome® TG H-ß-Ala-Gly-Arg-pNA · 2AcOH
081-66 Pefachrome® TH 8198 H-D-Phe-Pip-Arg-pNA · 2HCl  S-2238

Chromogenic Substrates for Factor Xa

 

085-01

 Pefachrome® FXa5277 CH3SO2-D-Leu-Gly-Arg-pNA · AcOH
085-03 Pefachrome® FXa5279 CH3OCO-D-CHG-Gly-Arg-pNA · AcOH
085-05 Pefachrome® FXa5112 C2H5OCO-D-Val-Gly-Arg-pNA · AcOH
085-06 Pefachrome® FXa CH3OCO-D-CHA-Gly-Arg-pNA · AcOH
085-26 Pefachrome® FXa8592 Cbo-Ile-Glu（γ-OR）-Gly-Arg-pNA · HCl （R=50% ME, 50% H）    S-2222
085-27 Pefachrome® FXa8595 Cbo-D-Arg-Gly-Arg-pNA · 2HCl S-2765

Chromogenic Substrates for Factor VII

 

093-01 Pefachrome® FVIIa CH3SO2·-D-CHA-Abu-Arg-pNA · AcOH

Chromogenic Substrates for Factor IXa

 

095-01 Pefachrome® FIXa3960 H-D-Leu-PHG-Arg-pNA · 2AcOH

 
095-02 Pefachrome® FIXa CH3SO2-D-CHG-Gly-Arg-pNA · AcOH

Chromogenic Substrates for Factor XIIa

 

092-02 Pefachrome® FXIIa H-D-CHA-Gly-Arg-pNA · 2AcOH

Chromogenic Substrates for Urokinase

 

082-01 Pefachrome® uPA Bz-ß-Ala-Gly-Arg-pNA · AcOH

 
082-02 Pefachrome® uPA5260 Cbo-Glu（OtBu）-Gly-Arg-pNA ·. AcOH

 

  
082-33 Pefachrome® uPA8294 pyro-Glu-Gly-Arg-pNA · 2HCl  S-2444

 

Chromogenic Substrates for Tissue Plasminogen Activator

 

091-01 Pefachrome® tPA CH3SO2-D-CHA-Gly-Arg-pNA · AcOH

 
091-03 Pefachrome® tPA5312 CH3SO2-D-Phe-Gly-Arg-pNA · AcOH

 

  
091-05 Pefachrome® tPA5314 CH3SO2-D-Abu-Gly-Arg-pNA · AcOH

 

Chromogenic Substrates for Plasmin

 

083-01 Pefachrome® PL5261 Tos-Gly-Pro-Lys-pNA · AcOH

 

  
083-02 Pefachrome® PL5262 H-D-But-CHA-Lys-pNA · 2AcOH

 

  
083-03 Pefachrome® PL5263 H-D-Nva-CHA-Lys-pNA · 2AcOH

 

  
083-04 Pefachrome® PL5264 H-D-Nle-CHA-Lys-pNA · 2AcOH

 

  
083-09 Pefachrome® PL5268 H-D-Ala-CHA-Lys-pNA · 2AcOH

 

  
083-14 Pefachrome® PL5272 H-D-Nle-CHA-Lys-pNA · 2HCl

 

Chromogenic Substrates for Glandular Kallikrein

 

088-01 Pefachrome® GK H-D-Val-CHA-Arg-pNA · 2AcOH

Chromogenic Substrates for Plasma Kallikrein

 

080-01 Pefachrome® PK 80714 Bz Pro-Phe-Arg-pNA · AcOH

 

  
080-03 Pefachrome® PK H-D-Abu-CHA-Arg-pNA · 2AcOH

 
080-08 Pefachrome® PK 8092Ca5295 H-D-Pro-Phe-Arg-pNA · 2HCl  S-2302

Chromogenic Substrates for Protein Ca

 

089-02 Pefachrome® PCa H-D-Lys（Cbo）-Pro-Arg-pNA · 2AcOH

 
089-03 Pefachrome® PCa5294 H-D-CHA-Pro-Arg-pNA · 2AcOH

 

  
089-04 Pefachrome® PCa5295 H-D-CHA-Pro-Arg-pNA · 2AcOH

 

  
089-07 Pefachrome® PCa5297 Pad-Pro-Arg-pNA · AcOH

 

  
089-08 Pefachrome® PCa3297 Pyr-CHG-Arg-pNA · AcOH

Chromogenic Substrates for the Determination of C1-Esterase

 

087-01 Pefachrome® C1E5292 C2H5CO-Lys（Cbo）-Gly-Arg-pNA · AcOH

 

  
087-02 Pefachrome® C1E5293 CH3OCO-Lys（Cbo）-Gly-Arg-pNA · AcOH

 

  
087-03 Pefachrome® C1E 5603 CH3CO-Lys（Cbo）-Gly-Arg-pNA · AcOH

Chromogenic Substrates for Trypsin

 

084-01 Pefachrome® TRY5274 Cbo-Val-Gly-Arg-pNA · AcOH

 

  
084-03 Pefachrome® TRY5276 Cbo-Gly-D-Ala-Arg-pNA · AcOH

 

  
084-04 Pefachrome® TRY Bz-Val-Gly-Arg-pNA · AcOH

 

Chromogenic Substrates for the Determination of Bacterial Endotoxins

 

086-01 Pefachrome® LAL5288 CH3OCO-D-CHA-Gly-Arg-pNA · AcOH

 

  
086-03 Pefachrome® LAL5290 CH3SO2·-D-Nle-Gly-Arg-pNA · AcOH

 

  
086-06 Pefachrome® LAL CH3SO2-D-CHA-Gly-Arg-pNA · AcOH

 

Other Chromogenic Substrates

 

083-05 Pefachrome® PL-Strept plasminogen-streptokinase complex H-D-Nle-CHA-Arg-pNA · 2AcOH

 
090-08 Pefachrome® ELA leucocyte elastase MeOSuc-Ala-Ala-Pro-Val-pNA

 
090-12 Pefachrome® PAP papain 3-Phenylpropionyl-Pro-Phe-Arg-pNA · AcOH

 

  
090-30 Pefachrome® Col collagenase （Clostridium histolyticum） Cbo-Gly-Pro-Leu-Gly-Pro-pNA

 
090-35 Pefachrome® Tryp Tryptase, Plasmin Tos-Gly-Pro-Lys-pNA · AcOH
 

Snake Venom Proteins

Activator Source Application Remarks  
 
113-01 / 113-04 Protac® • Determination of protein C and protein S
• Protein C pathway assays		 Serine protease Agkistrodon contortrix

 
116-01 Ecarin • Prothrombin assay
• Determination of hirudin		 Metalloprotease, activates specifically prothrombin via meizothrombin, does not need PL and Ca2+ Echis carinatus

 
119-02 Convulxin Activation of human plaets via binding and clustering of GPVI-receptors under physiological conditions Crotalus durissus

 
121-03 RVV Factor V-Activator Activation of FV in APC-R assay Serine protease, not inhibited by AT

 
121-06 RVV-X • Determination of FX
• Screening assay for lupus anti-coagulants （diluted Russel viper venom test, dRVVT）		 Metalloprotease, does also （weakly） activate protein C and factor IX Daboia （Vipera） russelli

 
800191 Pefakit® Reptilase® Time Ready-to-use diagnostic reagent for measurement of
• functionality of fibrin poly-merisation
• afibrinogenemia or hypofibrinogen-emia
• hyperfibrinolysis
• thrombolytic therapy		 CE-marked IVD Bothrops atrox
069-03 Prionex® （sterile hydrolyzed gelatine） Protein stabilization
116-10 HEPES-buffer Ecarin  
148-03 Gelatine 10% （solution） Protein stabilization  
801682 Rabbit Brain Cephalin Phospholipid source

Pefakit® APC-R Factor V

Pefakit® APC-R Factor V Leiden
Pefakit® APC-R Factor V Leiden is a plasma based functional assay for the determination of resistance of Factor Va to inactivation by activated protein C （APC） caused by the factor V Leiden mutation （FV:Q506）
 
Pack: 3 x 2 ml APC /RVV-V （+APC） Reagent
 
  3 x 2 ml RVV-V （-APC） Reagent
 
  3 x 4 ml PTA Reagent
 
  3 x 2 ml Dilution Plasma
 
REF: 502-01  
Pefakit® APC-R Factor V Leiden Controls
Control plasmas for confirmation of factor V Leiden mutation （FV:Q） in assays for determination of the functional phenotype for activated protein C resistance caused by the factor V Leiden mutation.
 
Pack: 3 x 1 ml FV-L Negative Control
 
  3 x 1 ml FV-L Heterozygous Control
 
REF: 502-21  
Pefakit® APC-R Factor V Leiden Homozygous Control
Control plasma for confirmation of factor V Leiden mutation （FV:Q） in assays for determination of the functional phenotype for activated protein C resistance caused by the factor V Leiden mutation.
 
Pack: 3 x 0.5 ml FV-L Homozygous Control
 
REF: 502-23  

Pefakit® Reptilase®Time

Pefakit® Reptilase®Time
For the investigation of the last phase of blood coagulation. Due to its heparin insensitivity the Reptilase®Time can detect fibrinogen polymerization disorders even in the presence of heparin.
 
Pack: 3 x 1 ml Reptilase®Time Reagent
 
REF: 800191  

Pefakit® in-TDT

Pefakit® in-TDT

Determination of initial thrombin formation by intrinsic activation.

Pack:                          2 x 2 ml             Reagent

                                   2 x 2 ml             Activator

                                   2 x 2,5 ml          Diluent

                                   1 x 1 ml             Calibrator

                                   1 x 1 ml             Control N

                                   1 x 1 ml             Control P                          

REF:                           800236

You can order your free manual and adaption protocol by clicking on the contact option on top of the screen.

– Manual for the Analysis Software Tool BCS®
– BCS Adaption protocol for Pefakit® in-TDT® Art. 800236

– Manual for the Analysis Software Tool ACL 9000
– ACL-9000 Adaption protocol for Pefakit® in-TDT® Art. 800236

Pefakit® PiCT®

Pefakit® PiCT® – Prothrombinase induced Clotting Time
Pefakit® PiCT® is a plasma based functional assay for the determination of factor Xa and factor IIa inhibitors.
 
Pack: 3 x 2 ml PiCT® Activator
 
  3 x 2 ml PiCT® Start Reagent
 
 
REF: 505-01  
 
Applications for various haemostasis systems on request
Applications for direct factor Xa inhibitors on request		  
Pefakit® PiCT® Calibrators UFH
 
Pack: 3 x 1 ml UFH Calibrator 1
 
  3 x 1 ml UFH Calibrator 2
 
 
REF: 505-121  
Pefakit® PiCT® Controls UFH
 
Pack: 3 x 1 ml UFH Control 1
 
  3 x 1 ml UFH Control 2
 
REF: 505-22  
Pefakit® PiCT® Calibrators LMWH
 
Pack: 3 x 1 ml LMWH Calibrator 1
 
  3 x 1 ml LMWH Calibrator 2
 
REF: 505-11  
Pefakit® PiCT® Controls LMWH
 
 
Pack: 3 x 1 ml LMWH Control 1
 
  3 x 1 ml LMWH Control 2
 
 
REF: 505-21  
Pefakit® PiCT® Calibrators Hirudin
 
 
Pack: 3 x 1 ml Hirudin Calibrator 1
 
  3 x 1 ml Hirudin Calibrator 2
 
REF: 505-13  
Pefakit® PiCT® Controls Hirudin
 
Pack: 3 x 1 ml Hirudin Controls 1
 
  3 x 1 ml Hirudin Controls 2
 
 
REF: 505-23  

Pefakit® TAFI