Multisciences 70-EK106

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Brand

MultiSciences

货号

70-EK106

品名

Human IL-6 ELISA Kit

海关名称:

Human IL-6 ELISA Kit

适用

ELISA 酶联免疫吸附测定

反应

Human

测定型

Sandwich ELISA 夹心酶联免疫分析

Suitable Sample Type

serum, plasma, cell culture supernates

适宜样本类型

96-well strip plate

贮存

4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)

装运条件

4℃

取样容积

50 μl

敏感,感受性

0.37 pg/ml

标准曲线范围

7.81 – 500 pg/ml

尖峰恢复范围

99 % – 115 %

平均尖峰恢复

1.06

CV of Intra plate

2.5 % – 5.0 %

CV of Inter plate

1.8 % – 4.4 %

成分

96-well polystyrene microplate coated with a monoclonal antibody against IL-6(96孔聚苯乙烯微板包覆抗IL-6单克隆抗体)

Human IL-6 Standard, lyophilized(人白细胞介素-6标准,冻干)

IL-6 Detect Antibody(IL-6抗体)

Standard Diluent(标准品稀释液)

Streptavidin-HRP(链霉亲和素)

Assay Buffer (10×)(分析缓冲液)

Substrate (TMB)衬底

Stop Solution(停止液)

washing Buffer (20×)(洗涤缓冲液)

Plate Covers(板盖)

描述

“This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human IL-6. The Human IL-6 ELISA is for research use only. Not for diagnostic or therapeutic procedures.(该方法采用定量夹心酶免疫分析法对人IL-6进行了定量检测。人IL-6酶联免疫吸附试验仅用于研究.不用于诊断或治疗 c程序。)

Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. In humans, it is encoded by the IL-6 gene. IL-6 is secreted by T cells and macrophages to stimulate immune response, e.g. during infection and after trauma, especially burns or other tissue damage leading to inflammation. IL-6 also plays a role in fighting infection, as IL-6 has been shown in mice to be required for resistance against bacteriumStreptococcus pneumoniae.

IL-6 stimulates the inflammatory and auto-immune processes in many diseases such as diabetes, atherosclerosis, depression, Alzheimer's Disease, systemic lupus erythematosus, multiple myeloma, prostate cancer, Behçet's disease, and rheumatoid arthritis. Advanced/ metastatic cancer patients have higher levels of IL-6 in their blood.”(白细胞介素-6(IL-6)是一种白细胞介素,它既是一种促炎细胞因子,又是一种抗炎性肌因子.在人类中,它是由IL-6基因编码的。IL-6由T细胞和巨噬细胞分泌。 HAGE刺激免疫应答,例如在感染期间和创伤后,尤其是烧伤或其他组织损伤导致炎症。IL-6在抵抗感染方面也起作用,因为IL-6具有B 表明小鼠对肺炎链球菌的耐药性是必需的。

 

IL-6可刺激糖尿病、动脉粥样硬化、抑郁症、阿尔茨海默病、系统性红斑狼疮、多发性骨髓瘤、前列腺等多种疾病的炎症和自身免疫过程。 癌症,贝塞特氏病和类风湿关节炎。晚期/转移性癌症患者血液中IL-6水平较高。)

 

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